Basic Information On Aromasin
Aromasin is used to treat estrogen dependent breast cancers in postmenopausal women. It lowers the levels of estrogen produced by the adrenal glands and reduces the growth of tumors. The Aromasin drug is mostly used as a second line treatment when other drugs have failed to contain the spread.
Precautions / Side Effects For Aromasin
Aromasin or Exemstane produces side effects that are directly linked to the reduction of estrogen levels. Hot flashes, headaches and joint pain are commonly encountered by women. These side effects are usually mild. Many women also experience moods swings and depression. Sleep disorders are also common. A complication that can develop due to brand or generic Aromasin treatment is osteoporosis which can lead to frequent fractures. Supplements to nourish and strengthen bones are prescribed to prevent this condition.
Exemstane is prescribed only for women post menopause as it acts on estrogen produced from the adrenal glands and not the ovaries (as in women who are still menstruating). It can impair reproduction in fertile women and can harm unborn babies. Liver problems have been associated with brand or generic Aromsin, but liver failure is rare. Individuals with liver metastases are more likely to have liver side effects which are evident from elevated levels of liver secretions in blood. The use of this drug, like other treatments for cancer, puts individuals at a slightly elevated risk for other cancers like that of the liver and kidneys. If you are on this medication for cardiovascular problems you have to report this to your doctor. Aromisin can cause changes in blood pressure and rarely heart conditions like a blockage.
Aromasin Dosage
The recommended dosage of Aromasin is one 25 mg tablet to be taken once every day after a meal. For patients suffering from advanced breast cancer, Aromasin treatment should continue till the tumor progression is evident. The recommended dosage of Aromasin for patients using potent CYP 3A4 inducer like phenytoin or rifampicin is 50 mg to be taken once daily after a meal. According to the experiments with exemestane at repetitive doses up to 200 mg every day that established a moderate increase in non-fatal adverse events, dosage of Aromasin did not appear to be changed or altered.
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