Basic Information On Avapro
Avapro drug is an anti-hypertensive agent and an antagonist of angiotensin II receptor. It is used in the treatment of hypertension. It can be used alone or as a combination therapy with other anti-hypertensive drugs as well. It is also used in the treatment of a condition called diabetic neuropathy in patients with type-2 diabetes and hypertension, who have an elevated creatinine level and proteinuria (< 300 mg/day). The drug acts by inhibiting the effects of angiotensin II. Angiotensin II is a vaso-constrictor that acts on vascular smooth muscles. Thus, the drug facilitates vasodilation. By blocking the effect of angiotensin II, brand or generic Avapro also blocks the synthesis of aldosterone, which is responsible for decreasing sodium excretion and increasing potassium excretion.
Precautions / Side Effects For Avapro
Common side effects of Avapro that you may experience are joint pain, stuffy nose, runny nose, cough, sore throat, heartburn, stomach pain, diarrhea, skin rashes, mild itching on the skin, anxiety, nervousness, dizziness, headache and feeling tired. Serious side effects that you may experience upon administering Irbesartan are difficulty in urinating, painful urination, chest pain, faster heart rate, swelling in the feet or hands and feeling like fainting (passing out). You must report these serious side effects to your health care provider and seek medical help.
Other rare but serious effect of Irbesartan are breakdown of skeletal muscle tissues that may lead to kidney failure. The drug may also cause muscle pain, muscle weakness or tenderness , especially if you already have nausea, vomiting, fever or dark colored urine. The drug may cause allergic reactions such as difficulty in breathing, hives, swelling in the throat, face, lips or tongue. If you experience any of these side effects upon administering Brand or generic Avapro then seek immediate medical help.
Avapro Dosage
In the treatment of hypertension the recommended dose of Avapro is 150 mg to be administered daily once. Drug dose may be adjusted for patients who need to reduce their blood pressure further. In such case the dose may be increased to 300 mg administered daily once. In patients with type-2 diabetes and hypertension, for treating diabetic neuropathy the recommended maintenance dose of Avapro drug is 300 mg to be administered daily once. In patients with depleted intra-vascular salt volumes an initial low dose of 75 mg of the drug is recommended. The drug may be administered with other anti-hypertensive agents with the doctor’s advice.
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