Basic Information On Cordaptive
Cordaptive is a cholesterol lowering drug. The drug is specifically suggested for use in cases when the patients have high amounts of LDL cholesterol and triglycerides but lower amounts of HDL or the good cholesterol. This drug is a combination of two chemicals, laropiprant and nicotinic acid (vitamin B3.) Nicotinic acid helps in reducing cholesterol; while laropiprant helps in reducing the flushes caused by niacin, it itself has no cholesterol lowering effect. According to research studies, Cordaptive drug can help lower cholesterol levels by almost 20 %.
Precautions / Side Effects For Cordaptive
If you have previously established allergies to the active ingredients of the drug, tell your doctor about it. Brand or generic Cordaptive is contraindicated in people with abnormal liver function tests, peptic ulcers, or arterial bleeding. So, discuss with your doctor if you suffer from any of these. The clear risks of using the drug during pregnancy are not known, hence, it should not be used during pregnancy unless clearly indicated. While taking this combination drug, some precautions can help in lowering the flushing effects of the vitamin. Do not take this medicine with hot beverages or alcohol, as that could increase flushing. Take care to let your doctor know of all your medications, as that will help him avert adverse drug interactions.
Some side effects associated with the use of Cordaptive include headache, pain in the back, and muscle weakness. In particular cases, people have also reported adverse reactions as dizziness, diarrhea, and pain in the chest and abdomen. If any of these persist, contact your doctor immediately. Niacin gets metabolized in the liver, which might increase the load on the liver and ultimately lead to jaundice or other kidney problems. Other side effects of nicotinic acid include itching and hot flashes.
Cordaptive Dosage
Cordaptive is available in the tablet form with strengths of 1000 mg of Niacin and 20 mg of Laropiprant. The usual trend is to start you off on a lower dosage to help the body get acquainted with the new compound. Hence, initial four weeks of lower dosage are followed by increased dosages depending on your reaction to the drug. However, the maximum dosage would not exceed more than two tablets daily. It has been indicated as unhealthy to increase the nicotinic acid amount by more than 500 mg in less than a month.
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