General Information on Dolobid
Dolobid is indicated for the treatment of mild to moderate rheumatoid arthritis and osteoarthritis. The active component in this drug, Diflunisal (also the generic name of Dolobid), has non-inflammatory properties. Dolobid falls under a category of drugs known as non-steroidal anti-inflammatory drugs or NSAIDs.
Diflunisal works by reducing pain, inflammation, and fever associated with the aforementioned conditions. It achieves this by reducing the production of prostoglandins, naturally-occurring chemicals that are responsible for inflammation, fever, and pain.
Dolobid is available in the form of oral tablets. In addition to Diflunisal, each oral tablet also contains the following excipients: FD&6 Yellow 6, magnesium stearate, cellulose, hydroxypropyl methylcellulose, talc, titanium dioxide, and starch.
Dolobid is listed as a prescription drug, meaning you should buy Dolobid only when your doctor prescribes it for your treatment.
Side effects of Dolobid
Common side effects of Dolobid are: epigastric distress (nausea, stomach upset, bloating, gas, diarrhea, or constipation), vomiting, mild headache, sleep problems, tiredness, ringing in the ears, or dizziness.
Less common but serious side effects of this drug include: speech problems, chest pain, vision or balance problems, tarry or black stools, coughing up of blood, dark colored vomit, unexplained or sudden weight gain, jaundice-like symptoms (low fever, dark urine, black or tarry stools, or yellowing of the eyes or skin), muscle weakness, less than normal or no urination, confusion, sore throat, or severe headache.
Dolobid may increase your risk to certain potentially fatal health conditions such as heart attack, circulation problems, or stroke. It is important that you discuss your medical history with your doctor before starting treatment.
Dolobid may cause potentially fatal side effects such as intestinal bleeding or perforation. It may occur suddenly and without warning. Geriatric patients are at increased risk to stomach bleeding or perforation due to Dolobid. You should consult your doctor immediately if you have any of the following symptoms: coughing up of blood, tarry, black, or bloody stools, or vomit that resembles coffee grounds.
Dolobid is a pregnancy category C drug, which means its safety in pregnant women has not been confirmed. If you are pregnant or planning to become pregnant, consult your doctor before using the drug. Your doctor will evaluate the benefits and risks associated with Dolobid before recommending it to you.
Dosage of Dolobid
The oral tablets are available in two strengths- Dolobid 250 mg and Dolobid 500 mg. Your doctor is likely to start with a lower dose and increase it gradually until the dosage that promotes the optimal response is not established. The dosage of Dolobid is established after taking into account certain factors such as the patient’s condition, response to treatment, medical history, and age.
For the treatment of rheumatoid arthritis, the recommended dose is Dolobid 500 mg – 1000 mg daily, administered as two divided doses.
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