Basic Information On Extavia
Extavia is an interferon drug. It is a naturally occurring protein synthesized in response to any viral infections (and/or biologic agents) by the eukarotic cells. The interferon helps in fighting against viral infections. The drug is used in the treatment of multiple sclerosis which relapses or recurs. It helps in reducing the frequency of exacerbations, especially in patients with first episode of multiple sclerosis. The precise mode of action of the drug is not known.
However, the brand or generic Extavia does not allow the immune cell activation (which attacks the myelin). Also, it induces suppression of the inflammatory cytokines production, which increases the inflammatory responses and thus the cytokines damage the myelin. The drug modulates the immune system and thus reduces the damage caused by inflammation.
Precautions / Side Effects For Extavia
Common side effects of Extavia include headache, weakness, muscle weakness, muscle pain, stomach pain, sleeping problems (such as insomnia), irregular menstrual periods, skin rashes and swelling in the feet or hands. If these side effects either prolong or worsen then consult your physician. Serious side effects of Interferon bets-1b include oozing, bruising, swelling or any kind of changes in the skin at the site where the injection is administered. Serious side effects may also include flu-like symptoms, body pain, chills or fever.
Other serious side effects of brand or generic Extavia are trouble in sleeping, anxiety, depression, mood changes, suicidal thoughts, thoughts of hurting oneself, feeling hot/ cold, pounding heart beats, changes in the weight, nausea, loss of appetite, stomach pain, dark urine, changes in the color of stools and jaundice-like symptoms such as eyes or skin turning yellowish in color. Before administering Interferon bets-1b let your physician know if you have thyroid disorder, liver disease, epilepsy, history of suicidal behavior or depression, anemia or bleeding disorders.
Extavia Dosage
The recommended dose of Extavia drug is 0.25 mg (1 mL) administered as subcutaneous injection, every alternate day. The dose of 0.25 mg is administered over 6 weeks period and not at once. In the 1st and 2nd weeks, 25% of the total dose (0.25 mg or 1 ml) is administered which is 0.0625 mg or 0.25 ml. In the 3rd and 4th weeks, 50% of the drug dose is administered which is 0.125 mg or 0.5 ml. In the 5th and 6th weeks, 75% of the drug dose is taken which is 0.1875 mg or 0.75 ml. 7th week onwards 100% of Extavia drug is administered which is 0.25 mg or 1 ml.
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Pharmacist Notes: Each kit contains 1 vial with powder and 1 pre-filled syringe with solvent. Each pack contains 15 kits.
