Basic Information On Exubera
Exubera is a rapid acting, powered human insulin which is genetically engineered (recombinant human insulin). The drug is used in adults for the treatment and management of type-1 and type-2 diabetes and is approved by the US FDA (Food and Drug Administration). In patients with type-1 diabetes the drug is used as a combination therapy along with other intermediate-acting or long-acting insulin types. In adult with type-2 diabetes brand or generic Exubera is used in patients whose diabetes is not controlled with orally administered anti-hyperglycemic drugs alone. Also it is used for insulin therapy in patients with type-2 diabetes who require insulin therapy. The drug when inhaled gets deposited into the lungs and then is absorbed in the body. Like the subcutaneous insulin Exubera drug also acts by inhibiting the glucose production by the liver. Thus, it results in reduction of the blood glucose levels.
Precautions / Side Effects For Exubera
Common side effects of Exubera are runny nose, stuffy nose, cough, sore throat, increase in sputum production, ear pain and dry mouth. If any of these common side effects prolong or worsen then consult your physician or health care provider. Serious side effects of the Insulin Human rDNA Origin include allergic reaction that is severe in nature such as difficulty in breathing, hives, rashes, tightness of chest, muscle pain, wheezing and swelling of the tongue, lips, mouth or face. If you experience these serious side effects then report the same to your physician or health care provider.
Other serious side effects of the Insulin Human rDNA Origin are chest pain, discomfort in the chest, changes in the vision, dizziness, drowsiness, confusion, chills, fainting, headache, irregular heartbeat, fast heartbeat, mood changes, unconsciousness, tremor, shortness of breath, trouble in breathing, seizures, slurred speech, unusual swelling, weakness, unusual hunger and trouble in concentrating. Most common side effect of brand or generic Exubera is hypoglycemia.
Exubera Dosage
The starting dosage of Exubera is calculated using the formula: body weight (kg) X 0.05 mg/kg = a pre-meal dosage (mg). The value of this formula is rounded off to the closest whole mg figure; for example 4.7 mg is rounded of to 4 mg. The approximate values of recommended dosage are as follows: for 30-39.9 kg body weight 1 mg/meal drug is administered, for 40-59.9 kg 2 mg/meal is administered, 60-79.9 kg 3 mg/meal, 80-99.9 kg 4 mg/meal, 100-119.9 kg 5 mg/meal and for 120-139.9 kg 6 mg/meal drug is administered. Approximately each blister of 1 mg of brand or generic Exubera is equivalent to 3 IU human insulin that is administered as subcutaneous injection. Also a blister of 3 mg is equivalent to 8 IU human insulin administered subcutaneously.
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