Basic Information On Pegintron
Pegintron is a pegylated interferon and is commonly used in the treatment of hepatitis C. It is also used in a combination therapy with ribavirin (Rebetol®). The drug is administered by patients who are 3 years of age or older, having compensated hepatic diseases. In the treatment of chronic hepatitis C it is also used as a monothearpy in patients who cannot tolerate ribavirin. As a monotherapy the drug is used only in patients who are 18 years of age and older. However, it is preferred that the drug is used as a combination therapy. Pegintron drug acts by facilitating the proliferation of the B cells which helps in increasing the production of antibodies. This allows the B cells to signal/inform the immune system about any foreign antigen that is present in the body.
Precautions / Side Effects For Pegintron
Common side effects that you many experience upon administering Pegintron are tired feeling, dizziness, sleep disorder (such as insomnia), loss of appetite, nausea, dry mouth, loss of weight, muscular pain, joint pain and headache. Other effects of the drug are mild anxiety, irritability and depression. It may also cause reddening, pain, irritation or swelling at the site of injection. Peginterferonum alfa-2b may also cause severe allergic reactions (such as hives).
You may experience serious side effects upon administering Peginterferonum alfa-2b which includes aggression, severe depression, severe anxiety, confusion, suicidal thoughts, thoughts of hurting yourself, headache, faster heart rate, uneven heartbeat, chest pain, fever, vision problems, body pain, pale appearing skin, flu-like symptoms, easy bleeding, easy bruising, unexplained weakness, diarrhea with blood, severe stomach pain along with high fever, nausea, vomiting, severe pain in the upper part of the stomach that spreads towards the back, sudden numbness, problem with balance or vision, shortness of breath and cough. Brand or generic Pegintron may also cause worsening hepatic symptoms.
Brand or generic Pegintron is administered as a subcutaneous injection only. As a combination therapy with 800 to 1400 mg of Rebetol (orally) the recommended dose of the injection is 1.5 mcg/kg/week in adults. In pediatric patients 60 mcg/m2/week of the drug is administered with 15 mg/kg/day of Rebetol orally. As a monotherapy Pegintron is administered is administered subcutaneously and the recommended dose of the injection is 1 mcg/kg/week. It is administered for a period of 1 year. Preferably, the drug is administered at the same day of the week (every week). The volume or amount of the drug injected depends upon the individual patient’s weight.
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