Basic Information On Pradaxa
Pradaxa is an anticoagulant or a drug that prevents blood from clotting. The main use of such drugs is for problems associated with blood clotting commonly called as thrombic disorders. The use of such drugs is also essential post operation to prevent unwanted clotting of blood. They are also used in applications like dialysis, where an individual’s blood is circulating outside the body and should not clot. Blood transfusion bags also require anticoagulants in order to ensure that the blood stays in the right composition. Anticoagulants work by preventing the action of an enzyme called thrombin. However, the main use of the Pradaxa drug is after surgeries, particularly after knee or hip replacement.
Side Effects/Precautions For Pradaxa
The side effects of Pradaxa or Dabigatran include bleeding for unknown reasons, stomach upsets and diarrhea. These side effects are mild compared to other anticoagulants but nevertheless they can be severe. The older population may face a bigger problem from these side effects. Also if you have any clotting disorders, you may not be prescribed this drug, as the effect of the drug could compound the pre existing problem resulting in excessive loss of blood, which has the potential to be fatal.
Dabigatran is usually not prescribed for individuals with renal problems as it can lead to toxicity. This also means that aged individuals may not be prescribed this drug as this population has a decreased renal function. However, its use may be determined on individual basis. Other anticoagulants may interfere with brand or generic Pradaxa. Pain killers and non steroidal anti inflammatory drugs NSAID can also worsen the side effects, particularly the side effects that are caused on the gastrointestinal tract. If you are pregnant, you need to let your doctor know about your condition. Continuing this medication during pregnancy is subject to your doctor’s approval.
Pradaxa Dosage
The dosage for normal adults is 110 mg given between 1 and 4 hours after surgery. Post surgery, the dose is increased to 220 mg and is continued for 10 days in case of knee replacement or 30 days in case of hip replacement. The dosage may be reduced to 75 mg if the renal function is supportive enough to clear the drug. However, if tolerance can be attained to higher dosage like 150 mg, then that dose is continued. The renal function is continuously monitored in order to avoid adverse effects.
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