Basic Information On Premarin Injection
Premarin Injection is a compound that is isolated from the mare’s urine. It is a mixture of hormones called estrogen (estrogen is a sex hormone, predominantly present in women). It is used intravenously as an injection and meant for short-term usage only. It is used for the treatment and management of abnormal bleeding of the uterus which may be caused because of hormonal imbalance. The drug is used to obtain rapid increase of the estrogen levels in the body but temporarily. Brand or generic Premarin injection is like hormone replacement therapy (HRT) and is most often used by post-menopausal women, especially women who have undergone hysterectomy. In such women the drug is used to treat burning, dryness or itching of the vagina and its surrounding areas.
Precautions / Side Effects For Premarin Injection
Common side effects of Premarin Injection are breast pain, swelling or tenderness of the breast, stomach cramps, bloating, vomiting, mild nausea, dizziness, headache, nervousness, increase in hair growth, loss of hair on the scalp, darkening or freckles on the facial skin, weight gain/loss, changes in appetite, vaginal discharge or itching, difficulties with contact lenses and feeling tired. Conjugated estrogens may also decrease in sex drive and changes in menstrual periods.
Serious side effects of brand or generic Premarin injection are heaviness of the chest, chest pain, breast lumps, nausea, pain that spreads to the shoulder or arm, sweating, sudden weakness or sudden numbness (especially on either side of the body), swelling or pain in the lower leg, sudden headache, trouble concentrating, problem with memory, problem with speech/ vision/ balance, confusion, abnormal bleeding from the vagina, swelling/ pain / tenderness in the stomach and swelling of feet/ ankles/ hands. Conjugated estrogens may also lead to jaundice like symptoms (skin or eyes becoming yellow).
Premarin Injection Dosage
The recommended dose of Premarin injection is one injection of 25 mg to be administered IV or intramuscularly. If rapid response is desired then IV is a preferred choice over other routes of administration. The drug should be administered slowly when taken IV, in order to avoid flushes. Based on the response of the patient the dose of the drug may be repeated after 6- 12 hours time. Premarin injection drug must be administered under medical supervision by the health care provider. It is not advisable to administer any other drug/ agent along with the drug through the IV infusion.
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