General Information on Proloprim
Proloprim, Trimpex and Primsol are the brand names of Trimethoprim. It is used to treat infections that are caused by some bacteria. Proloprim is an antibiotic that works by killing bacteria that are sensitive to this type of antibiotic medications.
You can only buy Proloprim as per a doctor’s prescription since it is a prescription drug.
Side effects of Proloprim
The side effects of Proloprim are:
- Dermatologic – rash which could range from morbilliform to pruritic and maculopapular, skin eruptions, and sensitivity of the skin to sunlight.
- Hypersensitivity- rarely reported exfoliative dermatitis, anaphylaxis, etc.
- Gastrointestinal- distress, vomiting, nausea, and glossitis.
- Hematologic- leucopenia, neutropenia, megaloblastic anemia, etc.
- Metabolic- hyperkalemia and hyponatremia.
- Neurologic- aseptic meningitis, which is rarely reported.
Proloprim can even lead to severe side effects for which patients have to seek immediate medical attention:
- Severe allergic reactions like rash, itching, breathing problems, tightness in the chest, or swollen face and throat.
- Decreased urination
- Joint pain
- Irregular heartbeat
- Painful or stiff neck
- Purple patches under the skin
- Unusual bleeding
Patients taking Proloprim may become sunburned more easily. Long-term use of this drug may lead to secondary infections. In the case of the elderly and children younger than 12 years of age, Proloprim should be used with extreme caution.
If you are pregnant or breastfeeding, it is best to consult a doctor before taking Proloprim.
Dosage of Proloprim
Proloprim should only be taken as directed by a doctor. The exact dosage instructions are, however, provided on the label.
The recommended dosage for adults is 100mg of Proloprim given every 12 hours. Alternatively, 200mg of Proloprim may be given every 24 hours.
You are not advised to buy Proloprim if you have a creatinine clearance of less than 15ml/min is not advisable. For patients with a creatinine clearance ranging from 15 to 30 ml/min, the dose should be Proloprim 50mg every 12 hours.
Proloprim should only be taken orally with or without food.
Proloprim works best if taken at the same time each day.
For overcoming the infection completely, the full course of Proloprim should be taken. The patient should use it even if there are significant improvements before the treatment finishes.
If a patient has just missed a dose of Proloprim, it may be taken at once. However, if it is nearly time for the next dose, you can skip the earlier one. Two doses should not be taken together.
An overdose of Proloprim can lead to dizziness, severe or prolonged headache, depression, sore throat, loss of consciousness, severe vomiting, etc. In such a case, immediate medical intervention is a must.
Interactions
Proloprim has been reported to have interactions with a total of 143 drugs. Among these five are major, 121 moderate, and 17 minor drug interactions. Drugs like baclofen, buprenorphine, lortab covering acetaminophen or hydrocodone, Lunesta (eszopicione), Lyrica (pregabalin), Macrodantin (nitroflurantoin), NegGram (nalidixic acid), Ritalin (methylphenidate), Sonata (zaleplon), Suboxone (buprenorphine or naloxone), and zaleplon interact adversely with Proloprim and must be avoided during treatment.
