Basic Information On Promacta
Promacta is a protein (man-made) which increases the platelet production in the body. It is used for the management and treatment of thrombocytopenia (a condition that is a result of low platelet count in the body). It is used especially in patients who have chronic ITP (immune thrombocytopenic purpura). The drug is administered only by those patients who are at higher risk of bleeding due to certain clinical conditions and thrombocytopenia. The drug is effective in patients who do not show sufficient response to the immunoglobulins, corticosteroids and splenectomy. Brand or generic Promacta is not a cure for thrombocytopenia. Also, it does not normalize the platelet count. It induces proliferation as well as differentiation of the megakaryocytes in the progenitor cells of the bone marrow.
Precautions / Side Effects For Promacta
Promacta drug may cause serious side effects which may include jaundice-like symptoms such as skin or eyes becoming yellow in color. You may also experience unusual bleeding (from the rectum, vagina, nose or mouth), easy bruising, darker appearing urine, clay colored stools, red/ purple color pin-point spots appearing under the skin, pain in the upper part of the stomach, loss of appetite, slight fever, nausea, eye pain, blurred vision and halos appearing around lights. Eltrombopag Olamine may also cause allergic reactions such as swelling of the lips, face, throat or tongue, hives and difficulty in breathing.
Common side effects of Promacta may include mild vomiting, mild nausea, stomach upset, reddening of the eyes, muscle pain, tingly feeling or numbness and heavy bleeding from the vagina. If any of these common side effects worsen or prolong, then consult your health care provider. Also, if you experience any of the above mentioned serious side effects or allergic reactions upon administering Eltrombopag Olamine, then seek medical attention immediately.
Promacta Dosage
The initial dosage of brand or generic Promacta is recommended as 50 mg to be administered once daily. However, for the patients who are of east-Asian ancestry (such as Japanese, Chinese, Korean or Taiwanese) the recommended initial dose is 25 mg administered once daily. In patients with hepatic impairment (moderate to severe) the recommended initial dose of Promacta is 25 mg administered once daily. The maximum recommended dose in any patient is 75 mg per day and should not be exceeded. To reduce the risk of bleeding, the dose of the drug should be adjusted and monitored in such a way that the platelet count is maintained at > 50x109/L.
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