Basic Information On Prostigmin
Prostigmin is a para-sympathomimetic drug. It is a muscle stimulant that is used in the treatment of diseases related to muscles, for example myasthenia gravis. The drug is also used in reversing or countering the effect of other muscle relaxants. The drug is an inhibitor of acetylcholinesterase. It interferes with the acetylcholine breakdown which is responsible for the relaxation of the muscles. It selectively acts on the skeletal muscles and does not affect the CNS (central nervous system). Thus the brand or generic Prostigmin triggers the contraction of skeletal muscles. In myasthenia gravis it is effectively used to improve the tone of the muscles. Additionally the drug is used in reversing the post-operative anesthesia effect of muscle relaxation.
Precaution / Side Effects For Prostigmin
You may experience common side effects of Prostigmin which appear in the beginning of the treatment. However these side effects subside over a period of time, as your body gets adjusted to the drug. These common side effects of Neostigmine may include dizziness, muscle cramps, increased urination, muscle twitching, drowsiness, vision changes, stomach upset, flatulence and flushing. Inform your health care provider or physician if these side effects worsen or prolong.
Serious side effects of Neostigmine include nausea, vomiting, diarrhea, severe pain in the stomach, increased salivation, sweating, weakness in the muscles, irregular heartbeats, difficulty in swallowing, speaking or breathing. If you experience any of these serious side effects then contact your physician. Let our physician know if you have had any of the following medical conditions in the past such as asthma, heart diseases, seizure disorder, thyroid disorder, ulcers, intestinal disorders, allergies (especially to bromides) or urinary problems. Pregnant and breast feeding women must administer Prostigmin drug only with the doctor’s advice.
Prostigmin Dosage
The average dose of Prostigmin is 150 mg (10 tablets) per day. It should be administered over a period of 24 hours. The dosing interval is of great importance and it varies from individual patient to patient. The therapeutic dose is determined by constant monitoring of a patient’s response and with the help of a physician. Usually, the required dose of brand or generic Prostigmin may vary from 15 mg to 375 mg in a day. A larger dose is given (preferably in the afternoons and evenings) to patients who experience fatigue. Although the drug takes time to work, its effects are long lasting.
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