General Information on Serzone
Serzone is an antidepressant drug. It effectively relieves depression symptoms such as feelings of guilt, sadness and worthlessness, loss of interest in daily activities, changes in appetite, insomnia, tiredness and thoughts of death. The generic name of this drug is Nefazodone.
Serzone acts by inhibiting CNS neuronal uptake of serotonin and norepinephrine. It also blocks 5-HT2 and Alpha 1 receptors. This medication is available as Serzone 50 mg, Serzone 100 mg, Serzone 150 mg, Serzone 200 mg and Serzone 250 mg.
Active ingredient of Serzone is Nefazodone hydrochloride and its inactive ingredients include microcrystalline cellulose, colloidal silicon oxide, povidone, sodium starch glycolate, magnesium stearate and iron oxides.
You can only buy Serzone as per a doctor’s prescription.
Side effects of Serozone
You should not buy Serzone online if you have:
- Hypersensitivity to Serzone or related compounds
- Taken a monoamine oxidase inhibitor like phenelzine, isocarboxazid or tranylcypromine in the last 14 days or currently taking astemizole, cisapride, pimozide, triazolam, or carbamazepine.
- Liver disease
- Family history of suicide attempts
- Seizures
Before you buy Serzone, inform your doctor if you have any of the following:
- Heart disease or irregular heartbeats
- Intestinal ulcers
- Extreme agitation
- Kidney disease
- Dehydration
Some of the common, and mild, side effects of this drug are:
- Dizziness, lightheadedness
- Stomach upset
- Abnormal vision
- Constipation
- Insomnia
- Dry mouth
You should consult your doctor immediately if your experience any of the following side effects:
- An allergic reaction
- Fainting
- Prolonged, inappropriate or painful erections
Pregnant women can use Serzone if recommended by their doctors. Nursing mothers should avoid this medication since it can pass into breast milk and may harm a nursing baby.
Dosage of Serzone
The recommended initial dose is 200 mg Serzone given daily and administered in two equally divided doses. The effective dose could vary from 300 mg Serzone to 600 mg Serzone a day.
The dosage for elderly or debilitated patients is 100mg Serzone a day administered in two doses. Usually there should be a gap of 2 weeks between discontinuation of an MAO inhibitor and initiation of Serzone therapy. Moreover, the inhibitor treatment can be restarted only if at least a week has passed after Serzone treatment ended.
In case of a missed dose, patient should take the missed dose as soon as he or she remembers. If it is almost time for next regularly scheduled dose, then a patient has to skip the missed dose. A patient has not to take extra medicine to make up the missed dose.
In case of an overdose of Serzone, symptoms such as nausea, drowsiness, seizures and vomiting may occur which need emergency medical care.
Interactions
There are 927 drug interactions, 1 food interaction and 4 disease interactions with Serzone. Drugs like terfenadine, astemizole, cisapride, carbamazepine, triazolam, pimozide should be avoided while taking Serzone since it leads to seizure, heart damage and even death. Many other dugs like haloperidol, alprazolam, lorazepam, tacrolimus, digoxin, warfarin, artovastatin, etc. also interact with this medication. Avoid alcohol since it may lead to excessive drowsiness.
