Tarceva (Erlotinib)

Basic Information On Tarceva

Tarceva is used to treat non small cell lung cancer, that is either locally advanced or has metastasized. It may be prescribed after the disease’s progression has not stopped with other chemotherapy medication or, it could be the first line of monotherapy. Studies support its use as first line monotherapy. The mechanism of action of the Tarceva drug is, inhibiting an important modification to the amino acid tyrosine. This drug is also used to treat pancreatic cancer that is locally advanced or has metastasized and even when surgery is not possible.

Side Effects / Precautions For Tarceva

Tarveca or Erlotinib is known to cause shortness of breath and cough. Lung interstitial disease, which is a broad range of lung disease and is different from obstructive diseases, is also a side effect. These diseases can make treatment difficult and can drastically affect the body as the immune system is weakened due to chemotherapy. The chances of fatality are very high with the occurrence of lung interstitial disease in patients undergoing treatment with brand or generic Tarceva. Many individuals also report skin side effects, like rash, itching and drying of skin. Skin rashes usually show up in 8 days after the treatment starts. Diarrhea is another common side effect.

Erlotinib can harm an unborn baby. Women are advised against getting pregnant during treatment, as the chances of fetal abnormalities and fatality is very high. Pregnancy also weakens the woman, already weakened due to chemotherapy. Individuals with liver problems are at a greater risk of hepatic failure due to treatment with brand or generic Tarceva, more so if there is liver metastasis. The chances of gastrointestinal perforation are high in individuals taking steroids or other medication. If such a condition is found to have developed, then this drug should be immediately stopped.

Tarceva Dosage

The recommended dose for treating non small cell lung cancer is 150 mg per day, taken on empty stomach an hour before food or two hours after a meal. The dose may be reduced to 100 mg or 50 mg, if lung side effects persist and worsen. If a lung interstitial disease has been diagnosed then chemo treatment is stopped and the other condition is treated. Dose reduction or treatment interruption may also become necessary if diarrhea does not respond to medication and the patient is dehydrated. Treatment may stop if hepatic or renal failure develops. For treating pancreatic cancer, the recommended daily dose is 100 mg.

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