Basic Information On Velcade
Velcade hampers the growth of certain cancer cells and restricts their spread in the body. Velcade is used for the treatment of mantle cell lymphoma and multiple myeloma. It is generally given to the patients when other cancer medications fail to work. This drug leads to lowering of blood cells that fight body infections. As a result, it may become easier for you to get sick by being around other ill people or bleed from an injury. While taking this medicine you should refrain from coming in contact with people who have flu, colds, or other contagious illnesses. You should avoid getting dehydrated if you have any diarrhea or vomiting.
Precautions/Side Effects For Velcade
You should consult your doctor before taking Velcade (Bortezomib) if you have diabetes, liver disease, if you are on dialysis, a blood clotting or bleeding disorder, low level of red or white blood cells or platelets, heart failure or any heart disease. FDA has categorized brand or generic Velcade as category D drug. Bortezomib can be harmful for an unborn child’s health. You should not take brand or generic Velcade if you are pregnant or intend to get pregnant. It is unclear if Velcade passes into breast milk. Therefore, you should consult your care provider before taking the drug, if you are breast feeding your child.
Side effects of Velcade drug are burning pain, numbness, weakness, feeling of faintness, dry cough and difficulty in breathing, problems with vision, severe headache, convulsions, confusion, tarry, bloody or black and severe constipation. Other side effects include easy bleeding or bruising, unusual weakness, body aches, fever, chills, flu symptoms, breathlessness, slow or fast heart rate, weak pulse, blood in urine, lower back pain and muscle weakness.
Velcade Dosage
The recommended dosage of Velcade is 3-5 second bolus IV injection which is given in combination with oral prednisone and oral melphalan for nine six-week treatment cycles. For the cycles 1-4, the drug is given 2 times weekly (that is on days 1, 4, 8, 11, 22, 25, 29 and 32). For cycles 5-9, it is given once weekly (that is on days 1, 8, 22 and 29). There should be a minimum gap of 72 hours between consecutive doses of Velcade. You should make sure that your platelet count is greater than equal to 70 x 109/L and the ANC is greater than equal to 1.0 x 109/L before stating the therapy.
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