Vincristine (Vincristine)

General Information on Vincristine

Vincristine is indicated for the treatment of non-Hodgkin’s lymphoma, Hodgkin’s disease, leukemia, Wilm’s tumor, neuroblastoma, and rhabdomyosarcoma. This drug may be used alone or along with other medications to treat the aforementioned conditions. You need a doctor’s prescription to buy Vincristine as it is a prescription drug.

Vincristine works by interfering with the growth of cancerous cells. It is meant for intravenous administration only. You are advised to receive the shot in a clinic or hospital setting as self-injection is not recommended. You can buy Vincristine single-use vials in Vincristine 1 mg/ml strength.

Side effects of Vincristine

Vincristine is contraindicated in patients who have:

• An allergy to any of constituents used in this drug
• A medical condition called Charcot-Marie-Tooth syndrome

Vincristine may cause serious side effects. The risk of these side effects may be increased for patients with certain medical conditions. Your doctor needs to know about your complete medical history before he/she can adjudge the treatment as safe. Tell your doctor if you have or have had:

• Myasthenia gravis, muscular dystrophy, Lou Gehrig’s disease (also known as ALS), or any other neuromuscular disorder
• Liver dysfunction or disease
• Any other major disorder

Serious side effects of Vincristine may include, but are not limited to, the following:

• Seizures
• Severe constipation
• Trouble breathing, chest tightness, wheezing
• Easy bruising, purple spots under the skin, unusual bleeding
• Trouble concentrating, lightheadedness, fast heart rate, pale skin, shortness of breath
• Tingling or burning feeling, numbness, pain
• Chills, white sores, or patches on the lips or inside the mouth, fever, mouth pain, sore throat
• Spinning sensation
• Vision, speech, balance or hearing problems
• Severe swelling, pain, redness, or burning at the administration site
• Yellow skin or eyes, loss of appetite, dark urine, stomach ache, low fever

Less serious side effects of Vincristine may include, but are not limited to, the following:

• Weakness
• Bone pain
• Jaw pain
• Temporary hair loss
• Diarrhea, vomiting, nausea

Dosage of Vincristine

The recommended dosage for adult patients is Vincristine 1.4 mg/m². Patients who have a direct serum bilirubin value in excess of 3 mg per 100 ml should be administered 50% of the recommended dosage.

The recommended dosage for pediatric patients is Vincristine 1.5-2.0 mg/m². The starting dose for pediatric patients who weigh 10 kg or less is Vincristine 0.5 mg/kg.

Interactions

Certain drugs may interfere with Vincristine. These include:

• Isoniazid
• AIDS or HIV drugs like nelfinavir, delavirdine, atazanavir, ritonavir, indinavir, saquinavir, or fosamprenavir
• Certain antidepressants
• Certain antibiotics like telithromycin, erythromycin, clarithromycin, or quinupristin
• Phenytoin
• Certain antifungal medicines like Voriconazole, clotrimazole, ketoconazole, or itraconazole
• Imatinib
• Diclofenac

Other drugs that are not listed above may also interact with Vincristine. Your doctor will know about all the drugs that have a potential to interact with this cancer medicine. As such, inform him/her about all other medicines that you are taking. This includes all prescribed, non-prescribed, and herbal drugs. Another thing you must do to prevent drug interactions during treatment is to consult your doctor before taking any new medication.

Patients who want to buy Vincristine online should purchase the drug only from a certified and reputed online prescription service.