Buy Femara from Canadian & International Pharmacies
Femara (Letrozole)and/or alternatives
Basic Information On Femara
Femara is used in the treatment of breast cancers that require estrogen to grow and divide. It belongs to a class of drugs called aromatase inhibitors. Aromatase is an enzyme that is required for the production of estrogen in the body. Estrogen in turn is essential for the growth of hormone sensitive cancer cells. Hence the Femara drug essentially cuts off the supply of estrogen to these malignant cells and slows the progress of the disease.
Precautions/Side Effects For Femara
Since Femara or Letrozole lowers estrogen in the body, its treatment results in side effects associated with lowered estrogen levels. These include hot flashes, frequent sweating, stomach cramps and feeling of redness of the face. Many women also feel agitated and are prone to drastic mood swings. Fatigue and nausea are also common. These symptoms usually subside with progression of the treatment but if they don’t, additional efforts may be needed to treat them.
Letrozole can cause fetal harm. Pregnant mothers are not prescribed these tablets as it can severely hamper fetal growth. Breast feeding mothers should discuss nurturing their infants with their doctors, as this drug can be passed into breast milk. Though there are no clear studies to establish the same, the risks should be debated. It is not advised to get pregnant during treatment with brand or generic Femara, and therefore, it is important that you use adequate contraception. The use of contraceptive pills must first be discussed, as those with hormone pills can cause adverse side effects. Any preexisting conditions of the liver or kidney may require dosage adjustment. Let your doctor know of any medication for these conditions. Many medications for cardiovascular problems are contraindicated.
The recommended dosage is 2.5mg per day taken for a period of about 5 years. This is the case if brand or generic Femara is used as adjuvant or extended treatment. In patients with first and second line treatment, the medication has to be continued till progression has stopped. If there is any evidence of relapse, the medication should be stopped and other modalities of treatment must begin. There is no need to adjust the dosage for treating individuals with mild hepatic impairment. However in patients with cirrhosis and severe hepatic impairment, the dosage is reduced to half. A 2.5 mg tablet is taken every other day.
Buy Femara From North Drug Store
The medication available with North Drug Store is Femara 2.5 mg. Since North Drug Store is a mail order online prescription service, you need to have no concerns when you buy Femara tablets.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.