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Nexavar (Sorafenib Tosylate)

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Full information about Nexavar

Basic Information on Nexavar

Nexavar is used in the treatment of advanced renal cell carcinoma (RCC), which is primary kidney cancer and hepatocellular carcinoma (HCC), which is advanced-primary liver cancer which cannot be removed surgically. The drug is sold as prescription drug. The drug is a multi-kinase inhibitor and targets a number of small molecules. The drug disrupts the kinases involved in the angiogenesis of multiple systems. Thus, the brand or generic Nexavar inhibits the division and growth of tumors or cancerous cells. It is suggested that this disruptive activity of the drug inhibits the growth of tumors. Kinase molecules play an important role in growth of various types of cancers. Therefore, the drugs that are used as kinase inhibitors in cancer therapy show better results.

Precautions / Side Effects for Nexavar

Common side effects with Nexavar are weight loss, fatigue, hypertension, hair loss, itching, rashes, dry skin, skin shedding, hand-foot skin reaction, constipation, nausea, vomiting, diarrhea, loss of appetite, abdominal pain, joint pain, dyspnea, headache, sensory neuropathy, hemorrhage, and bleeding events. Rare side effects of Sorafenib include discoloration of the skin to yellow color, reversible erythrocytosis, reversible leuko-encephalopathy, ulcers, severe discomfort, blisters, and moist desquamation.

In case of any rare adverse event, you must report to your physician or health care provider. Any rare reactions must be monitored closely along with the help of your health care provider. Pregnant women (and breast-feeding women) are not advised to administer the drug as it may lead to birth defects in the new born. Sorafenib shows drug-drug interactions with certain group of drugs such as flurouracil, docetaxel etc. Thus, before beginning the therapy do let our physician know about the current medications that you are taking. Nexavar drug is not meant for use in pediatric population.

Nexavar Dosage

The recommended daily dose of Nexavar is 400 mg. This is taken as 2x200 mg in tablet form, twice a day without food. The drug is administered at least one hour or two hours after a meal. Based on the response, effectiveness and the tolerability of the patient the dose may be adjusted. When the dose reduction is required, it may be reduced to 400 mg administered daily once. If further reduction of the dose is required then 400 mg of the drug may be administered every other day. The treatment with brand or generic Nexavar must be continued till the time the patient shows clinical benefits and should be stopped if toxicity occurs.

Buy Nexavar from North Drug Store

North Drug Store provides Nexavar drug at a fixed dose of 200 mg. By using our ease of ordering feature you can buy Nexavar and be assured of the confidentiality.

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