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Nexium (Esomeprazole)and/or alternatives
Basic Information About Nexium
Nexium which belongs to the drug group “proton pump inhibitors” (PPIs) is used to treat gastroesopahageal reflux disease (GERD) and Zollinger-Ellison syndrome. Esomeprazole reduces gastric acid secretion in the stomach walls by inhibiting H+/K+ ATPase, proton pumps, in the gastric parietal cell. By acting on the proton pump, Nexium inhibits the last step in the production of acid, thus curbing gastric acidity. It is a powerful, predictable and long lasting cure for GERD. It heals esophagus, damaged by excessive stomach acid and also helps cure gastric ulcers caused by non steroidal anti inflammatory drugs (NSAID) or infection with helicobacter pylori. The Nexium drug significantly saves medical resources and patient suffering by cutting down on endoscopic retreatment, blood transfusions, and length of hospital stay due to re-bleeding.
Precautions/Side Effects of Nexium
As Nexium contains esomeprazole, it should not be taken by patients allergic to esomeprazole or to any other benzimidazole medication while those with liver disease need dose adjustment. You should not tamper with the medication schedule. Brand or generic Nexium is used in combination with antibiotics for treatment of certain conditions; therefore, it is most essential to take esomeprazole as per doctor’s directions. Certain symptoms may improve before the disease is fully cured but you should be careful not to leave the treatment halfway and take medication for full prescribed length of time.
As initial symptoms for both heartburn and heart attack and are often confused. You are therefore advised to pay urgent attention if you experience chest pain or a feeling of heaviness, pain spreading to the arm or shoulder, sweating, nausea and a general ill feeling. Pregnant and breast feeding women must intimate the doctor about the condition even though brand or generic Nexium is not known to harm the baby or pass into breast milk.
Dosage of Nexium
Nexium should be taken an hour before meals and the dosage varies according to age and weight of the patient. A short term treatment of 4 to 8 weeks is recommended for confirmed erosive esophagitis. The dosage may be extended for another 4 to 8 months if required. However, it doesn’t extend beyond 6 months. The Nexium delayed release capsules can be administered by dissolving into water or even apple sauce, if the patient has trouble swallowing capsules. For patients with a nasogastric tube in place, the capsules can be released into the tube with a catheter tipped syringe.
Buy Nexium From North Drug Store
North Drug Store provides tablets (20mg) and injections (40mg X 5 ml) of brand or generic of Nexium (Esomeprazole). To buy Nexium rely on the confidentiality and fast shipping that North Drug Store provides and order today.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.