Buy Tarka from Canadian & International Pharmacies
Tarka (Trandolapril/Verapamil)and/or alternatives
Basic Information On Tarka
Tarka is a combination drug that is prescribed for hypertension or high blood pressure. It consists of an ACE inhibitor that inhibits the function of an enzyme that converts one form of the hormone angiotensin to another form. This constricts blood vessels and affects an increase in blood pressure.
Side Effects / Precautions For Tarka
Severe side effects of Tarka or Trandolapril/Verapamil include reduced urination and in some individuals it may stop completely. This is a dangerous condition as it can affect the kidneys, result in unwarranted blood pressure changes and also lead to sepsis. You may also notice changes in your heart rate, which has a bearing on your daily normal activity; you may feel tired with little or no exertion at all. Chest pain is another side effect. Jaundice is reported as a common liver related side effect caused by brand or generic Tarka tablets. Less serious side effects, which usually go away after a tolerance is built, include diarrhea, constipation, headache, joint and back pain.
Women are not advised to get pregnant during treatment with Trandolapril/Verapamil, as it is known to cause fetal injury. If you are pregnant, stop using the drug and contact your doctor immediately. It is also known to be excreted in the breast milk. So before breastfeeding discuss the risks associated with breast feeding with your doctor. If you are on medication for kidney or liver disease, then you may not be prescribed this medication. Diabetes and heart failure patients should inform their status to their doctors before beginning treatment.
The treatment with brand or generic Tarka starts only after monotherapy with each of its constituents fail, or dose increase of individual constituent doses, cannot be made. The recommended starting dose is 2 mg of Trandolapril and 120 mg of Verapamil. The total dose can be taken in two divided doses. The increase in doses can be up to 4 mg for Trandolapril and upto 480 mg for Verapamil. For those who are replacing individual medication, the same doses can be used. This drug should be administered with food. Dose dependent side effects may warrant reduction of doses. Individuals with renal, hepatic and heart problems need dose adjustments if they have to be prescribed this drug.
Buy Tarka From North drug Store
The lowest prices are guaranteed when you buy Tarka. The required number of Tarka 2/180, 2/240 or 4/240 mg can be ordered easily.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.