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Viagra (Sildenafil)and/or alternatives
Basic Information On Viagra
Viagra is used to treat erectile dysfunction in men with functional reproductive organs. It works by preventing certain substances from lowering the effect of nitric oxide in the penis, which is responsible for smooth relaxation and healthy erection, when a man is sexually stimulated. The Viagra drug at recommended doses is not effective without sexual stimulation. Since this drug essentially improves blood flow, the same chemical composition can be used for treatment of pulmonary arterial hypertension in men and women.
Side Effects/Precautions For Viagra
Side effects of Viagra or Sildenafil which usually don’t require medical attention or treatment include redness of the face or chest, stuffed nose and headache. These problems are caused due to changes in blood pressure. The warmth that you may feel when you take this drug is also due to enhanced blood supply to your body. When the effect of brand or generic Viagra starts to wear off, these side effects also disappear. As your body gets used to the drug and builds tolerance, the side effects reduce in intensity.
You may not be prescribed Sildenafil if you have any cardiovascular problems like high blood pressure, a recent history of heart attack and bleeding disorders like hemophilia. Some men are also advised against sexual activity for health reasons. Such individuals should not take brand or generic Viagra. You need medical attention if you notice any sudden changes in your vision or if the erection is painful and last for longer than 4 hours. Men with deformities in the penis are not prescribed this drug. If you have any liver or kidney disease, then you must mention these to your doctor before you start taking this drug.
The recommended dosage is 50 mg, that can be taken anywhere between 30 minutes and 4 hours before sexual activity. If satisfactory response has not been achieved, then the dose can be increased up to a maximum of 100 mg. It can also be decreased to 25 mg if required. Viagra should not be taken more than once a day. Individuals with renal or hepatic impairment are prescribed a dose of 25 mg. Dose increases are not considered, unless satisfactory renal and hepatic health has been achieved. Lower dose of 25 mg is also prescribed for men older than 25 years, if there are no kidney or liver problems.
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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.