Buy Tygacil from Canadian & International Pharmacies
Tygacil (Tigecycline)and/or alternatives
Basic Information On Tygacil
Tygacil is an injectable glycylcycline antibacterial drug. It is a semi-synthetic derivative of minocycline. This medication acts against tetracycline-resistant gram-positive and gram-negative pathogens. It is used to treat infections of the skin, soft tissues and intra-abdominal infections caused by susceptible bacteria. It is injected intravenously. The Tygacil drug attaches to bacterial ribosomes and stops the production of proteins required for the growth and multiplication of the bacteria. This medicine is also able to overcome typical bacterial resistance to tetracyclines. Its modification at position 9 of its core structure, gives additional steric hindrance to it. Therefore, Tygacil has a much wider range of activity than conventional tetracyclines. However, it only prevents multiplication of the bacteria; it does not kill the bacteria.
Precautions / Side Effects Of Tygacil
Tygacil contains Tigecycline. It should not be administered to patients hypersensitive to Tigecycline or other tetracycline class antibiotics. It is structurally similar to tetracycline-class antibiotics and may cause adverse side effects like: anti-anabolic action (which has led to increased BUN, azotemia, acidosis, and hyperphosphatemia), photosensitivity, and pseudotumor cerebri. Using this drug during tooth development can cause permanent staining or discoloration of teeth. Brand or generic Tygacil should not be given to patients below 18 and breast feeding women.
In isolated cases, brand or generic Tygacil may lead to hepatic dysfunction and hepatic failure. Special caution should be exercised while administering this medication to patients with liver disorders. Its effects may persist even after the medication has been discontinued. Tigecycline should be used only in treating infections strongly suspected to be caused by susceptible bacteria. Using this drug may also result in the overgrowth of non-susceptible organisms like fungi. This medication must not be used by pregnant women as it can injure the fetus.
The recommended initial dosage for Tygacil is 100 mg. It is followed by a 50 mg dose every 12 hours. Intravenous infusions of this medication should be administered over 30 to 60 minutes at intervals of 12 hours. For the treatment of severe intra-abdominal infections or skin and skin structure infections this medication should be given for 5 to 14 days. For the treatment of community-acquired bacterial pneumonia, the duration of treatment should be 7 to 14 days. The medication dosage should be adjusted for patients with severe hepatic impairment. The duration of treatment is based on the severity and the site of infection. It also depends on the patient’s clinical and bacteriological improvement.
Buy Tygacil From North Drug Store
North Drug Store supplies brand or generic Tygacil as 50 mg injections. You can buy Tygacil from North Drug Store, as we are a online prescription service and offer a low price guarantee.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.