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Aggrenox (Dipyridamole/Acetylsalicylic Acid)

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Full information about Aggrenox

Basic Information On Aggrenox

Aggrenox is vasodilator and is used to decrease the risk of strokes in patients with prior history of transient ischemia in the brain. It is also effective in patients with thrombosis leading to ischemic stroke. The drug has multiple mechanisms of action. It acts by inhibiting thromboxane synthase which helps in reducing the effects of TXA2; these effects include bronchio-constriction, vaso-constriction and platelet aggression. It also blocks the reuptake of adenosine into the RBCs, endothelial cells and platelets, thus, it increases the concentration of extracellular adenosine. Also, it inhibits the breakdown of adenosine to inosine and increases the adenosine concentration. This increase of adenosine concentration in the coronary circulation causes vasodilatation. Brand or generic Aggrenox relaxes the arteriolar smooth muscles.

Precautions / Side Effects For Aggrenox

You may experience certain common side effects with Aggrenox drug which include joint pain, headache, drowsiness, stomach upset, nausea, vomiting, mild heartburn and diarrhea. Serious side effects of the drug may include fainting, weakness, coughing out blood, vomit that appears like coffee grounds, stools appearing black, tarry or bloody, swelling for more than 10 days, pain for more than 10 days, ringing in the ears, hearing problems, severe nausea or vomiting, severe stomach pain and fever for more than 3 days. Upon administering ASA/Dipyridamole if you experience these serious side effects then consult your physician immediately.

Brand or generic Aggrenox shows several drug-drug interactions with other class of drugs; for example, orally administered medication for diabetes, acetazolamide, medications for gout, ACE inhibitors, medications for Alzeimer’s disease, medications for seizures, diuretics, NSAIDs etc. Thus, let your doctor know about all the medications you are currently taking before administering ASA/Dipyridamole. Inform your doctor if you have prior history of liver or kidney disease, low blood pressure, heart diseases, bleeding disorder (like hemophilia) or stomach bleeding and/or ulcers.

Aggrenox Dosage

The standard dose of Aggrenox is recommended as 1 capsule to be administered twice daily. The drug is administered orally, one dose in the morning and second dose in the evening. The dose may be adjusted based on the patient’s response and tolerability. If the signs of intolerance are seen, such as headaches, then the dose is reduced to only 1 capsule a day. This one capsule is to be administered at bed time. Once these effects subside, the usual regimen of Aggrenox drug must be continued. Any dose changes must be done with the advice of the health care provider.

Buy Aggrenox From North Drug Store

Buy Aggrenox at a fixed dosage of 200/25 mg from North Drug Store and be assured of on time supply.

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