Buy Anafranil SR from Canadian & International Pharmacies
Anafranil SR (Clomipramine Hydrochloride SR)and/or alternatives
Anafranil SR 75mg from $0.62 USD/tabletAnafranil SR 75mg
Manufactured by: Novartis
Product of Turkey. Shipped from TurkeyRxPrescription Required
Clomipramine Hydrochloride SR 75mg from $0.42 USD/tabletClomipramine Hydrochloride SR 75mg
Generic Alternative to Anafranil SR
Marketed as Clofranil SR in India
Manufactured by: Sun Pharma
Product of India. Shipped from IndiaRxPrescription Required
Basic Information On Anafranil SR
Anafranil SR is called a tri-cyclic anti-depressant (TCA) agent. It is primarily used in the treatment and management of obsessive compulsive disorder (OCD). It is effective in patients who demonstrate obsession and compulsions. Besides this, the drug is also used in the treatment and management of various other conditions such as panic disorder, major depression, narcolepsy, de-personalization disorder, premature ejaculations, cataplexy and enuresis (urinating in the night sleep involuntarily) in adolescents and children. It is also used in treating chronic pain which may include headache associated with tension, pain associated with organic disease or pain in general. Brand or generic Anafranil SR acts by preventing the reabsorption or reuptake of neurotransmitters called nor-adrenaline and serotonin. These neurotransmitters are mood elevators. This action of the drug helps to lighten the mood for a longer period of time.
Precautions / Side Effects For Anafranil SR
Common side effects of Anafranil SR include dry mouth, drowsiness, headache, dizziness, confusion, anxiety, sleep disturbances, disturbances/changes in the taste, blurred vision, constipation, vomiting, nausea, sweating, change in appetite, difficult urination (or urine retention), sexual problems, hot flushes, weight gain, tremors and tinnitus (ringing in the ears). It may also cause twitching or other involuntary muscle movements. Other side effects of Clomipramine may include convulsions, abnormal heart beat, postural hypotension, which is drop in the blood pressure while sitting down, lying down or standing. The drug is not recommended for children below 18 years of age.
If you are allergic to any TCAs then avoid Anafranil SR drug. Also, before administering the drug let your physician know if you have any heart defect, heart block, recent heart attack, arrhythmias (irregular heartbeat), severe hepatic diseases, hypokalamia (low blood potassium level), glaucoma, urine retention or mania. Also let your doctor know if you are currently administering monoamine-oxidase inhibitor anti-depressants before taking Clomipramine.
Anafranil SR Dosage
The initial dosage of Anafranil SR is as 25 mg per day. The drug is administered preferably during the bedtime. This helps in reducing the sedation effects during the daytime. Based on the tolerability of the patient, the dose is increased to 100 mg in adults and 3 mg/kg or 100 mg (whichever is lesser) in children during the first 2 weeks period. Thereafter, the dose of Brand or generic Anafranil SR may be increased to a maximum of 250 mg per day in adults and 3 mg/kg or 200 mg (whichever is lesser) in children, gradually in the following several weeks.
Buy Anafranil SR From North Drug Store
The drug is available in fixed dose of 75 mg. Buy Anafranil SR from North Drug Store and be assured of the punctual time supply and confidentiality.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.