Buy Factive from Canadian & International Pharmacies
Factive (Gemifloxacin Mesylate)and/or alternatives
Factive 320mg from $12.24 USD/tabletFactive 320mg
Manufactured by: Abdi Ibrahim
Product of Turkey. Shipped from TurkeyRxPrescription Required
Basic Information On Factive
Factive is a broad-spectrum antibiotic and belongs to fluoro-quinolone class of drugs. It is used in the treatment of various bacterial infections. The drug is used in the treatment of pneumonia (mild to moderate in severity) and chronic bronchitis which is caused due to acute exacerbation of the bacteria. It is effective against S. pneumoniae, Moraxella catarrhalis, Haemophilus parainfluenzae and Haemophilus influenza strains. The drug is also effective in the treatment of pneumonia (mild to moderate in severity) which is community acquired and caused by the strains mentioned above as well as Chlamydia pneumoniae, Mycoplasma pneumoniae and Klebsiella pneumoniae. Brand or generic Factive acts by inhibiting the enzymes topoisomerase-II and IV responsible for DNA replication, recombination, repair and transcription of bacteria. Thus the drug blocks the bacterial growth.
Precautions /Side Effects For Factive
Common side effects of Factive are nausea, diarrhea, drowsiness, stomach upset, dizziness, loss of appetite, headache, altered taste, dry mouth, constipation and troubled sleeping. Serious side effects of Gemifloxacin are swelling or pain of joints, muscles and tendon, tendon rupture, sun burn (sensitivity to sun), vision changes, chest pain, dark urine, variations in the volume/amount of urine, easy bleeding, easy bruising, fast heartbeat, irregular heartbeat, fainting, sore throat, seizures, fever, unexplained fatigue, persistent vomiting or nausea and skin or eyes appearing yellow. Serious side effects of Factive drug also include mood changes or mental changes for example severe depression, suicidal thoughts etc.
If you experience these serious side effects then consult your physician immediately. If you use Gemifloxacin for a long period of time then you may experience new vaginal or oral fungal infections. You may experience vaginal discharge or patches in the mouth. In this case seek medical attention. Also report the serious allergic reactions such as hives, itching etc to your doctor.
The standard recommended dose of Factive is 320 mg per day. In the treatment of chronic bronchitis due to acute bacterial-exacerbation the dose is 320 mg tablet daily once, for 5-days. In the treatment of community-acquired pneumonia (mild to moderate) for strains K. pneumoniae and M. catarrhalis 320 mg tablet is taken once daily for 7-days and for any other strains it is taken for 5-days. For patients with creatinine clearance < 40 mL/min the recommended dose is 160 mg administered every 24 hours. The dose regimen of brand or generic Factive is determined based on sputum culture done prior to the therapy.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.