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Integrilin (Eptifibatide)

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Full information about Integrilin

General Information on Integrilin

Integrilin is a blood thinning drug, or an anticoagulant, and is used for preventing blood clots that can lead to severe blood circulation problems or heart attack. Integrilin is used prior to performing certain procedures to open blocked vessels and arteries in the heart, such as angioplasty or coronary stent placement.

Integrilin is also used with certain other drugs to prevent a cardiovascular attack in patients who suffer from continuous chest pain but cannot undergo procedures required for opening up blocked arteries in the heart.

The generic name of Integrilin is Eptifibatide. It works by preventing platelets from binding with each other. You need a doctor’s prescription to buy Integrilin as it is a prescription based drug.

Integrilin is meant for intravenous use only. Do not administer Integrilin through an intramuscular or subcutaneous injection. The drug is available in two strengths, Integrilin 0.75mg/ml and Integrilin 2mg/ml. In addition to Eptifibatide, the drug contains the following ingredients (inactive): water for injection, citric acid, and sodium hydroxide.

Side effects of Integrilin

Common and less serious side effects of this drug may include:

  • Upset stomach
  • Nausea
  • Mild pain, redness, swelling around the IV infusion site

Rare but serious side effects of Integrilin may include:

  • Easy bruising or unusual bleeding
  • Blood in the urine
  • Tarry, black, or bloody stools
  • Vomit that appears similar to coffee grounds or blood stained sputum
  • Sudden weakness or numbness
  • Body aches, fever, flu symptoms, chills
  • Severe headache
  • Vision, balance, or speech problems

You should consult your doctor if during treatment you experience any side effect that appears severe or causes concern.

You should not buy Integrilin if you have a known allergy to any of its constituents. Integrilin is contraindicated in patients have or have/had any of the following:

  • Abnormally low platelet count
  • A blood clotting disorder
  • Severe liver disorder
  • Abnormally high blood pressure
  • Stroke
  • Severe injury or surgery in the last 6 weeks
  • An internal bleeding in the last 30 days
  • A brain tumor

Integrilin comes under pregnancy category B. That is, it is not expected to cause any harm to the unborn child. Still, you must always consult your doctor before using this blood thinner if you are pregnant.

The safety of Integrilin in breastfeeding women has not been established. Consult your doctor if it is safe to breastfeed during the treatment.

Dosage of Integrilin

Your doctor will recommend you the correct dosage after studying your condition, medical history, other drugs that you are using, and response and tolerance to Integrilin. Your doctor may prescribe other drugs to be used in conjunction with Integrilin. It is necessary that you take all prescribed medications on time and for as long as the prescribed treatment plan states.


Certain drugs, when taken along with this blood thinner, may decreases the effectiveness of Integrilin, increase the risk of certain side effects, or lead to certain potentially dangerous interactions. Names of some such drugs include, but are not restricted to, the following:

  • Alteplase, urokinase, tenecteplase, and other drugs used for dissolving blood clots
  • Anagrelide, ticlopidine, prasugrel, dipyridamole, cilostazol, and other drugs that clumps platelets together
  • Argatroban, lepirudin, dabigatran, bivalirudin, and other drugs that inhibits the activity of an enzyme that is responsible for blood clotting
  • Warfarin or other blood thinners

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