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Isoptin (Verapamil Hydrochloride)

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Full information about Isoptin

General Information on Isoptin

Isoptin, with the active ingredient verapamil hydrochloride, is used for treating high blood pressure, heart rhythm disorders, and chest pain. The generic name of this drug is Verapamil. This drug falls in a category of drugs referred as calcium channel blocker, or CCB.

Isoptin works by relaxing the arterial muscles. It is meant for oral use only and is available in following strengths: Isoptin 40 mg, Isoptin 80 mg, Isoptin 120 mg, and Isoptin 240 mg. You should buy Isoptin only if your doctor prescribes it for your treatment.

Side effects of Isoptin

You should not buy Isoptin if:

  • You have a known hypersensitivity to verapamil or any other ingredient present in it
  • You have low blood pressure
  • You have serious heart conditions like AV block (unless you are using a pacemaker) or sick sinus syndrome
  • You recently suffered a cardiovascular attack

Before you start treatment, speak to your doctor about the potential risks of using Isoptin in your particular case. During treatment, if you experience any side effect(s) that causes concern, immediately report it to your doctor. A partial list of possible side effects of Isoptin is presented below.

Less severe side effects of Isoptin may include the following:

  • Nausea
  • Constipation
  • Tired feeling, dizziness, or mild headache

Severe side effects of Isoptin may include the following:

  • Slow or fast heartbeats
  • Sudden and unexplained weight gain
  • Swelling
  • Sore throat, severe headache, fever
  • Loss of appetite, dark-colored urine, tarry or black-colored stools, yellowing of the eyes or skin, low fever, nausea
  • Prior to starting treatment, you must share your complete medical history with your doctor. Your doctor may ask you to undergo certain tests to ensure the drug is completely safe for you or may adjust your dosage if you suffer from any of the following conditions :

    • Liver disease
    • Kidney disease
    • Congestive heart failure
    • Muscular dystrophy or any other nerve-muscle disorder

    The safety and effectiveness of Isoptin in pregnant and lactating women has not been confirmed. Consult your doctor before using Isoptin if you are pregnant or breastfeeding.

    Dosage of Isoptin

    The recommended starting dosage for treating hypertension is Isoptin 80 mg three times a day. Depending on patient’s response the dosage may be gradually increased. Daily maintenance dosage should not exceed Isoptin 480 mg.

    The recommended starting dosage for treating angina pectoris is Isoptin 80 mg three times a day. Depending on patient’s response the dosage may be gradually increased. Daily maintenance dosage should not exceed Isoptin 480 mg.

    The recommended starting dosage for treating obstructive hypertrophic cardiomyopathy is Isoptin 80 mg three times daily. Depending on patient’s response the dosage may be gradually increased.

    The actual dosage may vary from patient to patient. It is important that you take your medication exactly as prescribed by your doctor.

    Interactions

    Various drugs can interact with Isoptin. Shared below is a partial list of such drugs:

    • Beta-blockers such as sotalol, timolol, atenolol, bisoprolol, and others
    • HIV medicines such as nelfinavir, delavirdine, ritonavir, and others
    • Heart rhythm medicines such as quinidine, amiodarone, disopyramide, and others
    • Cancer medicines such as procarbazine, cyclophosphamide, vinorelbine, and others
    • Theophylline
    • Certain antibiotics such as rifampin, erythromycin, clarithromycin, and others
    • Antifungal medicines such as voriconazole, itraconazole, fluconazole, and others
    • Simvastatin or lovastatin
    • Digoxin
    • Cyclosporine

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