Buy Kaletra from Canadian & International Pharmacies
Kaletra (Lopinavir/Ritonavir)and/or alternatives
Kaletra 200/50mg from $7.91 USD/tabletKaletra 200/50mg
Manufactured by: Abbott Laboratories Ltd.
Product of Canada. Shipped from CanadaRxPrescription Required
Lopinavir/Ritonavir 200/50mg from $2.53 USD/tabletLopinavir/Ritonavir 200/50mg
Generic Alternative to Kaletra
Marketed as Lopimune in India
Manufactured by: Cipla
Product of India. Shipped from IndiaRxPrescription Required
General Information on Kaletra
Kaletra is used in treatment of HIV infections, which may result in AIDS (acquired immune deficiency syndrome). The drug is not intended to cure HIV or AIDS, but to prevent HIV cells from multiplying in the body. It may be used alone or in conjunction with other HIV medications as part of HIV/AIDS treatment.
The drug is a combination of two medications, Lopinavir and low dose Ritonavir. Lopinavir belongs to a group of medicines known as protease inhibitors. It inhibits activity of HIV protease, a chemical essential for HIV cells to multiply. Ritonavir suppresses the metabolism of Lopinavir which helps in keeping increased levels of Lopinavir in the blood.
Kaletra is available in the form of a tablet and an oral solution. The tablets are available in two strengths which are color coded for easy identification. The yellow tablet contains 200mg of Lopinavir and 50mg of Ritonavir while the pale yellow colored tablet contains 100 mg of Lopinavir and 25 mg of Ritonavir. The oral solution contains 80 mg Lopinavir and 20 mg Ritonavir per milliliter.
Kaletra is a prescription medication and may cause side effects if used for unintended purposes. Therefore, you should buy Kaletra only on doctor’s recommendation.
Side effects of Kaletra
Kaletra may cause mild to severe side effects in some people. Vomiting, weakness, tingling or numbness, especially around the mouth, mild nausea, bloating, mild skin rashes, stomach pain, mood changes, diarrhea, headache, changes in location of body fat ( especially in your neck, arms, face, legs, waist or breast) are some less severe side effects associated with Kaletra.
Some people may also experience severe side effects such as headache with severe blistering, easy bleeding/bruising, fever, skin rashes, peeling of the skin, extreme thirst, increased urination, sore throat, severe pain in upper stomach that spreads to back, dark urine, vomiting, low fever, clay colored stools, or yellowing of the eyes or skin. Consult your doctor immediately if you notice or experience any severe side effects after taking a dose of Kaletra.
Dosage of Kaletra
Your doctor will give you specific recommendations regarding the use of the drug. Doctors generally recommend patients to take this medication once or twice daily. You can take the medication with or without food, but it is advisable to take the tablet with a light snack or meal.
If you are using other medicines then there is a possibility that Kaletra may interact with them and cause side effects. It may interact with medications such as Bosentan, Colchicines, Fluticasone, Salmeterol, Rifabutin, Itraconazole, Ketoconazole, Voriconazole, Bupropion, Trazodone, Warfarin, cancer medications such as Nilotinib or Dasatinib, cholesterol-lowering medications such as Atorvastatin, Rosuvastatin, Cyclosporine, Tacrolimus, heart or blood pressure medications such as Amlodipine, Diltiazem, Nifedipine, Verapamil,and, and others, heart rhythm medicines such as Amiodarone, Quinidine.
Kaletra may also cause side effects by interacting with Insulin or diabetes medication taken orally, narcotic medicines such as Methadone, Fentanyl, seizure medicines such as Phenytoin, Carbamazepine, Phenobarbital, Sildenafil, Vardenafil, Tadalafil and other HIV /AIDS medications such as Nelfinavir, Efavirenz, Nevirapine, Fosamprenavir and others.
Before you buy Kaletra, tell doctor about every medication are using. Tell him/her about prescription drugs, over the counter medications, and herbal supplements you are using.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.