Buy Kemadrin from Canadian & International Pharmacies
Kemadrin (Procyclidine Hydrochloride)and/or alternatives
Kemadrin 5mg from $0.37 USD/tabletKemadrin 5mg
Manufactured by: GlaxoSmithKline UK Ltd
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
Kemadrin 2.5mg from $0.16 USD/tabletKemadrin 2.5mg
Manufactured by: GSK Pharma
Product of India. Shipped from IndiaRxPrescription RequiredCurrently Unavailable
Procyclidine Hydrochloride 5mg from $0.75 USD/tabletProcyclidine Hydrochloride 5mg
Generic Alternative to Kemadrin
Manufactured by: A UK MHRA approved Generic Manufacturer
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
General Information on Kemadrin
Kemadrin is indicated for the treatment of Parkinson's disease. It is also used to manage extrapyramidal side effects (such as involuntary body and face movements, restlessness or tremors) caused by antipsychotic medications. The drug is not intended to cure Parkinson’s disease, but only to provide relief from some of its symptoms.
Procyclidine Hydrochloride, the main active ingredient in the medication belongs to a class of drugs known as anticholinergic. It prevents Acetylcholine (a neurotransmitter) from binding to brain cell receptors, which reduces the effect of Acetylcholine.
Normal muscle movements depend on balance of two neurotransmitters, Dopamine and Acetylcholine. People with Parkinson’s disease have low levels of Dopamine which creates an imbalance. Procyclidine Hydrochloride tries to restore the balance between neurotransmitters by blocking the effects of Acetylcholine.
Kemadrin is available in the form of a tablet. The drug is a prescription medication which means you should buy Kemadrin and use it only if your doctor has recommended it in your treatment.
Side effects of Kemadrin
Kemadrin may cause mild to severe side effects in some people. Red swollen gums, dry mouth, constipation, problems with memory and understanding, blurred vision, nausea, vomiting, anxiety/nervousness/agitation, hallucinations, mental confusion, rashes, difficulty passing urine and disorientation are some side effects associated with Kemadrin.
The side effects mentioned above generally occur only when you take higher doses of Kemadrin. These side effects can be treated easily by lowering the dose. Kemadrin may also cause severe allergic reactions, such as a swollen mouth, face, throat, or lips, skin rashes, hives or itching. Consult your doctor immediately if you notice or experience side effects or allergic reactions after taking a dose of Kemadrin.
Pregnant women, women who plan to get pregnant, nursing mothers should learn about the risks and benefits associated with the drug before buying and using the medicine.
Dosage of Kemadrin
Your doctor will give you specific instructions regarding the dosage. Never take medication in larger quantity than recommended by your doctor. Each Kemadrin tablet contains 5mg of Procyclidine hydrochloride.
The recommended starting dose for adults with Parkinson’s disease is half tablet (equivalent to 2.5mg) three times a day. Doctor may increase the dose by 2.5mg to 5mg daily every 2-3 days until patients gets relief from Parkinson’s disease symptoms. Your doctor may recommend a long term dose of 15mg to 30mg daily to manage the symptoms.
The recommended starting dose to manage side effects of Neuroleptics medication in adults is 2.5mg, three times a day. Doctor may increase the dosage by 2.5mg each day until patient gets relief from the symptoms. The long term effective dose to manage symptoms is in the range of 10mg-30mg daily.
If you are using other medicines then Kemadrin may potentially interact with them and cause side effects. It may interact with medications such as Monoamine oxidase inhibitors, Paroxetine, Phenothiazines, Neuroleptics, Antihistamines, medicines used to treat nausea and gastric reflux, Levodopa, Amantidine, Quinidine.
To reduce the risk of side effects due to drug interactions, tell doctor about every medication you are using before starting the treatment. Tell him/her about prescription medicines, over the counter drugs and herbal supplements you are using before you buy Kemadrin tablets.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.