Shipping Update - May 1 2022

Shipping times are now closer to normal. However, due to the latest outbreak of the highly contagious Omicron strain, some delays in shipping times may still occasionally occur. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Shipments may sometimes take an additional 2 weeks to arrive, depending on the source country of your order.

Please note that these times are averages and individual shipping times will vary. We recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

Call Center – New Hours effective April 1, 2022

Our call center hours of operation are now 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.

Management and Staff
Affordable Drugs

Buy Letairis from Canadian & International Pharmacies

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Letairis (Ambrisentan)

and/or alternatives
Letairis is not available. Letairis is a brand name for Ambrisentan. Other generics of Ambrisentan are available below.
Generic OptionsWhat is a Generic?

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Shipping is $10.00 per order. All prices are in USD. Average shipping time is 2 weeks.
Full information about Letairis


Letairis (ambrisentan) is a prescription drug to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the lung arteries. Women who are prescribed Letairis must not get pregnant or breastfeed, as ambrisentan can cause serious birth defects. You may also be prescribed Tadalafil as a companion drug.

The proceeding text is for informational purposes only. North Drugstore is an online Canadian and international prescription service that sources medication from dispensaries all over the world. We do not supply any medication without a prescription. Only your doctor or healthcare provider may prescribe Letairis or any other medication. If you have questions about your Letairis prescription, consult the product information or speak to your doctor.

About Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension causes high blood pressure, which the World Health Organization has categorized into four classes of severity, Class I being mild with no physical limitations, Class IV being severe without any ability to perform physical activities. Letairis is intended for people with WHO Group 1 PAH who experience Class II symptoms. If you think you have PAH, speak to your doctor. Left untreated, PAH can get worse. Your doctor will schedule a series of tests to determine the cause of your high blood pressure. These tests include:

  • Chest x-ray
  • Echocardiogram
  • Electrocardiogram
  • Right heart catheterization
  • Blood tests

About Letairis

It has been proven that when Letairis and Tadalafil are taken together, patients with PAH experienced greater benefits, such as doubling their ability to walk long distances, reducing their chance of their PAH getting worse, and reduce rate of hospitalization for PAH. Taken alone Tadalafil is taken to treat pulmonary arterial hypertension to improve your capacity to exercise. Speak to your doctor about the benefits of pairing Letairis and Tadalafil.

Take your Letairis medication as directed. Letairis may react with other medications, so make sure to tell your doctor about other prescription drugs you are taking, including vitamins and herbal supplements. If you forget, take your Letairis medication as soon as you remember. If it’s close to your next scheduled dose, skip the dose. Do not take a double dose to catch up. Do not take Letairis unless it was prescribed to you, even if you are experiencing similar symptoms to PAH. Discuss with your doctor what other measures you can take to lower your high blood pressure, such as certain lifestyle changes.

Important Safety Information about Letairis

The following is taken from the product’s official website and is not a complete list of safety information. For a full list, consult with your doctor or the product literature. Not all safety information regarding pregnancy is listed.

Letairis can cause serious birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking Letairis or become pregnant while taking Letairis
  • Females who are able to get pregnant must have a negative pregnancy test before starting Letairis, every month while taking Letairis, and 1 month after stopping Letairis. Your doctor will decide when to do the tests, and order the tests for you depending on your menstrual cycle
  • Tell your doctor right away if you miss a menstrual period or think you may be pregnant
  • Females can only receive Letairis through a restricted program called the Letairis Risk Evaluation and Mitigation (REMS) program. If you are a female who can get pregnant, you must talk to your doctor, understand the benefits and risks of Letairis, and agree to all of the instructions in the Letairis REMS program.

Do not take Letairis if:

  • You are pregnant, plan to become pregnant, or become pregnant while taking Letairis. Letairis can cause serious birth defects. (See "What is the most important information I should know about Letairis?")
  • You have Idiopathic Pulmonary Fibrosis (IPF)

What should I avoid while taking Letairis?

  • Do not get pregnant. If you miss a menstrual period, or think you might be pregnant, call your doctor right away
  • Do not breastfeed. It is not known if Letairis passes into your breast milk.

Possible Side Effects

This is not the full list of possible side effects. For a full list, consult the product literature or ask your doctor. According to the official Letairis website, Letairis can cause these side effects if taken alone, such as:

  • Swelling of hands, legs, ankles, and feet (peripheral edema)
  • Headache
  • Stuffy nose (nasal congestion)
  • Cough
  • Low red blood cell levels (anemia)
  • Indigestion (dyspepsia)
  • Upper respiratory tract infection (bronchitis)

If taken with Tadalafil, the following side effects may occur:

  • Swelling of hands, legs, ankles, and feet (peripheral edema)
  • Stuffy nose (nasal congestion)
  • Inflamed nasal passages (sinusitis)
  • Hot flashes or getting red in the face (flushing)

More serious side effects can occur, such as:

  • Swelling all over the body (fluid retention) can happen within weeks after starting Letairis. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital.
  • Decreased sperm counts (fluid retention) can happen within weeks after starting Letairis. Tell your doctor right away if you have any unusual weight gain, tiredness, or trouble breathing while taking Letairis. These may be symptoms of a serious health problem. You may need to be treated with medicine or need to go to the hospital.
  • Low red blood cell levels (anemia) can happen during the first weeks after starting Letairis. If this happens, you may need a blood transfusion. Your doctor will do blood tests to check your red blood cells before starting Letairis. Your doctor may also do these tests while you are taking Letairis.

Order Letairis at Your Online Canadian & International Prescription Service

North Drugstore prides itself on its efficiency and quality service. We source medication from international dispensaries to find the most affordable prescription drugs for our customers. We provide our customers with affordable brand name prescription drugs and their cheap generic alternatives.

Now you can order your Letairis prescription Online! North Drugstore’s hassle-free online prescription service delivers cheap prescription medication right to your door. Shop for Letairis medication Online and save.

* All trademarks and registered trademarks are the property of their respective owners.

IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.