Buy Marquis Paste from Canadian & International Pharmacies
Marquis Paste (Ponazuril)and/or alternatives
Marquis 150mg/g from $262.25 USD/syringeMarquis 150mg/g
Manufactured by: Bayer Inc
Product of Canada. Shipped from CanadaRxPrescription RequiredCurrently Unavailable
General Information on Marquis Paste
Marquis Paste is used for treating equine protozoal myeloencephalitis, or EPM, caused due to Sarcocystis neurona. The medicine is meant to be given to horses.
Active ingredient in the medicine is Ponazuril, and it belongs to the class of anticoccidial or antiprotozoal compounds with activities against different genera of phylum Apicomplexa.
It is given to the horse in the form of an oral paste. It is available in ready-to-use syringes so that its administration is made easier. The medicine works by reaching the parasite’s central nervous system, killing them at any stage of their lives.
Side effects of Marquis Paste
The veterinarian will not recommend you to buy Marquis Paste if your pet has allergy to Ponazuril, or if it is meant for food. Before starting treatment with Marquis Paste, make sure that the horse is not suffering from any other disease such as in-coordination, which has almost same signs as EPM.
Also inform the veterinarian if your horse is pregnant, lactating or breeding, as special adjustments may be needed during or before the treatment.
Because the medicine is not meant for human consumption, you should not give it to your horse if you are going to use it for food. Avoid getting the medicine ingested into your system, as severe reactions may take place. Do not smoke, eat or drink anything while handling the medicine, as it may accidentally get ingested by you.
Some of the side effects associated with Marquis Paste include hives, rashes, diarrhea, blisters, seizures or signs of mild colic. Notify the veterinarian immediately if your horse encounters any of these symptoms, as some adjustments may need to be made.
Some horses may also develop an allergic reaction to the medicine. Signs of an allergy include hives, facial swelling, shock, sudden onset of diarrhea, scratching, cold limbs, coma, seizures or pale gums. Contact the veterinarian at once if your pet encounters any of these symptoms.
Dosage of Marquis Paste
The veterinarian will advise you to give Marquis Paste 5mg per kg of the horse’s body weight once in a day, for 28 days.
Before administering the paste into the horse’s mouth, you need to make sure that there is not remaining feed in the pet’s mouth. Because each paste tube contains multiple doses, you have to measure the dose correctly and ensure that you are giving the right dose to your pet.
Once you have deposited the paste in your horse’s mouth, raise its head immediately for a few seconds so that the paste can be swallowed completely.
Drug Interactions of Marquis Paste
The veterinarian will not recommend you to buy Marquis Paste if your horse is allergic to the medicine, or if you are already giving it other medicines to treat the same condition.
You must also tell the veterinarian about all the prescription and non-prescription veterinary drugs you are giving to your pet at present, including herbal preparations and nutritional or health supplements. Depending on these, the veterinarian will be able to decide whether this medicine is the right product for your pet or not.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.