Buy Megace from Canadian & International Pharmacies
Megace (Megestrol Acetate)and/or alternatives
Megace 160mg from $2.87 USD/tabletMegace 160mg
Manufactured by: Bristol Myers Squibb
Product of Turkey. Shipped from TurkeyRxPrescription Required
Megestrol Acetate 20mg from $0.29 USD/tabletMegestrol Acetate 20mg
Generic Alternative to Megace
Manufactured by: A US FDA approved Generic Manufacturer
Product of United StatesRxPrescription RequiredCurrently Unavailable
Megestrol Acetate 160mg from $2.28 USD/tabletMegestrol Acetate 160mg
Generic Alternative to Megace
Marketed as Borea in Turkey
Manufactured by: Onko
Product of TurkeyRxPrescription RequiredCurrently Unavailable
General Information On Megace
Megace is an oral medication which contains megestrol acetate, a synthetic alternative of the naturally occurring steroid hormone, and progesterone. The generic name of Megace is megestrol. The medication is used for the treatment of advanced carcinoma of the breast and endometrium. It is also prescribed to increase appetite and prevent weight loss in various conditions. Though it is not known how the drug boosts appetite, Megace can lead to high blood sugar if used for this purpose.
The exact mechanism of how Megace brings about antineoplastic effects against endometrial carcinoma is yet to be discovered, but it is speculated that a decrease in estrogen secretion and pituitary gonadotropin production are the factors responsible for it. The medication not only curbs the growth of hormone dependent breast cancer cells, but is also capable of eliminating and modifying the stimulatory effects of estrogen on those cells.
Megace has a direct effect on the lining of the uterine wall as well, so a patient must buy Megace only if prescribed, and it should be administered under the supervision of a doctor. The medication in the form of an oral suspension consists of inactive ingredients like purified water, sodium citrate, sucrose, citric acid, alcohol, lemon-lime flavor, xantham gum, sodium benzoate, and polysorbate 80, and 40mg of micronized megestrol acetate as the main ingredient.
A patient should consult his/her doctor if he/she has any allergies to the ingredients in Megace to prevent severe allergic reactions. One must also inform the doctor about his/her medical history, especially if he/she has diabetes, blood clots, congestive heart failure, high blood pressure, kidney problems, unusual vaginal bleeding, and adrenal gland problems.
Side Effects of Megace
Megace, like many other drugs, has its share of side effects, the severity of which varies from person to person. There have been reports that the use of Megace can lead to thromboembolic phenomena, including thrombophlebitis and pulmonary embolism.
Weight gain is one of the most common side effects of Megace It is directly associated with increased appetite, though it is not necessary that such weight gain is also associated with fluid retention.
A patient should contact his or her doctor in case he or she experiences any of the following side effects:
- Fast heartbeat
- Swelling in the hands and feet
The major side effects of Megace are:
- Tumor flare
- Nausea and vomiting
- Heart failure
- Mood changes
Dosage of Megace
The recommended dosage of Megace for adults varies depending on the condition being treated. For the treatment of breast cancer the recommended dose is 160 mg perday. For the treatment of endometrial carcinoma 40-320 mg per day is given to the patient in divided doses. When used as a therapy for anorexia, cachexia, or an unexplained weight loss in patients with acquired immunodeficiency syndrome (AIDS) the dosage is Megace 800mg per day, and if taken in the form of an oral suspension, the recommended dose is 20 ml per day. Doctors may recommend daily doses of 400 and 800 mg a day as per a patient’s individual condition.
Megace can interact with several drugs and lead to complications. The medications that react with Megace include:
- Immunosuppressive medications like immunomodulators/efalizumab.
- Natalizumab megestrol/dofetilide.
Inform your doctor about all the prescription, over the counter, and herbal drugs or supplements you are using before you buy Megace.
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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.