Buy Norflex from Canadian & International Pharmacies
Norflex (Orphenadrine Citrate)and/or alternatives
Norflex 100mg from $0.79 USD/tabletNorflex 100mg
Manufactured by: iNova
Product of New Zealand. Shipped from New ZealandRxPrescription Required
Norflex 100mg is also available from CanadaNorflex 100mg from $1.32 USD/tabletNorflex 100mg
Manufactured by: Graceway Pharmaceuticals
Product of Canada. Shipped from CanadaRxPrescription Required
Orphenadrine Citrate 100mg from $1.06 USD/tabletOrphenadrine Citrate 100mg
Generic Alternative to Norflex
Marketed as Sandoz-Orphenadrine in Canada
Manufactured by: Sandoz
Product of Canada. Shipped from CanadaRxPrescription Required
General Information on Norflex
Norflex is an antagonist used for the treatment of Parkinson’s disease caused due to drug induction and for treating painful muscles. The generic name of this drug is Orphenadrine. Norflex acts as a relaxant for skeletal muscles, helping to reduce pain in turn relaxing the muscles. This is a prescribed medicine and you can buy Norflex from a local pharmacist only by showing your doctor's prescription.
The main component of Norflex is Orphenadrine Citrate. Each tablet contains 100mg of this active ingredient. Orphenadrine is also used for the treatment of patients suffering from bladder neck obstruction, glaucoma and prostatic hypertrophy as it displays certain anticholinergic activity.
Dopamine is a substance that carries messages in between two particular parts of brain. This act in turn allows smooth movement of human body muscles. A lack of Dopamine results in the movement-related symptoms that are witnessed in a patient suffering from Parkinson's disease. Due to low levels of Dopamine, the communication between the two parts of the brain is disrupted and the movement of muscles is hindered.
Norflex acts as a binder for both NMDA receptors and histamine H1 receptors. The stimulating effects of cholinergic system increase due to the lack of dopamine in striatum. Orphenadrine has an anticholinergic effect, which counteracts the stimulation caused by dopamine deficiency. It relieves muscle spasms and elevates the mood of the sufferer.
Other than Orphenadrine Citrate, Norflex also contains the following ingredients - Magnesium Stearate, Lactose, Ethylcellulose and Colloidal Anhydrous Silica.
Side Effects of Norflex
The side effects commonly encountered by patients using Norflex include
- blurred vision, dilated pupils
- tremors, anxiety, confusion, hallucinations, agitation
- drowsiness, dizziness
- dry mouth or throat
- rapid or uneven heartbeats
- nausea, vomiting, constipation
- seizure (convulsions)
- reduced or no urination
For further details about potential side effects you may refer to your physician or pharmacist or read the information leaflet you receive when you buy Norflex
You may not take Norflex if you have ever had any of the following conditions:
- Allergy from Orphenadrine Citrate of any such similar medications or any other ingredients of Norflex.
- If you are suffering from glaucoma or high pressure in the eye
- If you are suffering from intestinal blockage, esophageal disease or stomach ulcer
- If you are a patient of bladder obstruction or enlarged prostate
- If you are suffering from myasthenia gravis
- If the expiry date of the medicine has passed
- If there are any signs of tampering on the packaging
Children under the age of 12 years shall not take Norflex.
Dosage of Norflex
For adults, the usual prescribed dosage of Norflex is one tablet, two times in a day. For correct dosage, consult your doctor. Take Norflex according to the prescription of your doctor. Do not alter the dosage on your own.
Norflex is said to interact with total 692 drugs. These drugs tend to increase the side effects of Norflex and may reduce its efficacy. It is advisable to tell your doctor about all the medications you have undertaken in past or you are currently taking, before starting a course of Norflex.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.