Buy Norpace CR from Canadian & International Pharmacies
Norpace CR (Disopyramide Phosphate CR)and/or alternatives
Norpace CR 250mg from $1.29 USD/tabletNorpace CR 250mg
Marketed as Rythmodan Retard in European Union
Manufactured by: Sanofi Aventis
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
General Information on Norpace CR
Norpace CR (controlled release) is prescribed for the treatment of serious irregular heartbeats like persistent ventricular tachycardia. The generic name of this drug is Disopyramide and it falls under a class of drugs referred as anti-arrhythmic drugs.
Norpace CR blocks electric signals that cause irregular heartbeats. This drug is administered orally and is available in two strengths, Norpace CR 100 mg and Norpace CR 150 mg.
The inactive ingredients present in 100 mg and 150 mg CR capsules are: corn starch, edible ink, ethylcellulose, sucrose, gelatin, shellac, titanium dioxide, and talc.
Side effects of Norpace CR
You should not buy Norpace CR if you are allergic to Disopyramide. The use of Norpace CR may not be the best option in certain medical conditions, such as myasthenia gravis, glaucoma, and kidney disease, enlarged prostate or liver disease. Before you buy Norpace CR, ensure that you inform your doctor about your medical history, especially if you have or have had any of the aforementioned conditions.
Some of the less serious side effects of this drug may include: blurred vision, mild headache, dizziness, mild rash, tiredness, difficulty urinating, muscle aches, or dry mouth.
Consult your doctor if you experience any of the following serious side effects while using Norpace CR: severe dizziness, worsening or new irregular heartbeats, chest discomfort, chest pain, swelling of the legs or feet, or symptoms of an hypersensitivity reaction (such as hives, severe skin rashes, facial flushness, difficulty breathing, or closing of the throat)
Other side effects of Norpace CR may also occur in rare cases. To know more about the side effects of this drug, read the patient information leaflet or consult your pharmacist or doctor.
Dosage of Norpace CR
The dosage of Norpace CR depends on patient’s weight, tolerance, and response to the treatment. For most adult patients with body weight equal or more than 110 pounds, the recommended daily dosage is Norpace CR 600 mg administered in two equal dosages at a gap of 12 hours. The recommended dosage for adults with body weight less than 110 pounds is Norpace CR 200 mg administered in two equal dosages every 12 hours.
The recommended dosage in patients suffering from moderate renal insufficiency is Norpace CR 400 mg administered in two equal dosages every 12 hours.
Certain drugs if taken in combination with Norpace CR may decrease its efficacy or increase the risk of some side effects. Patients are advised that they inform their physician or pharmacist, in advance, advance about all other drugs that they are presently taking. This includes herbal as well as non-prescription medicines. It is also important that, during treatment with Norpace CR, you consult your doctor before starting any new medication.
Here are the names of some drugs that are likely to interact with this anti-arrhythmic medicine:
- Beta-blockers (for example propranolol, acebutolol, nadolol, metoprolol, labetalol, carteolol, pindolol, and others)
- Other drugs used for treating irregular heartbeat (for example procainamide, quinidine, amiodarone, bepridil, and others)
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.