Buy Oforta from Canadian & International Pharmacies
Oforta (Fludarabine Phosphate)and/or alternatives
Fludara 10mgFludara 10mg
Manufactured by: Genzyme Canada Inc.
Product of Canada. Shipped from CanadaRxPrescription RequiredCurrently Unavailable
Basic Information On Fludara
Fludara treatment is given as an intravenous injection to treat CLL (B-Cell chronic lymphocytic leukemia) and other cancers. CLL is a type of cancer which advances slowly resulting in abnormal proliferation of white blood cells called lymphocytes. The medicine is meant only for adults whose disease has advanced or who have not reacted to treatment with any standard alkylating agent for their cancer. Fludara retards and may stop the growth of cancer cells. It is an antimetabolite which interferes with the cancer’s ability to multiply and also causes “Cell suicide” in the cancer cells. Due to the kind of structure of the active ingredient Fludarabine phosphate, it is capable of bypassing action of adenosine deaminase enzyme and getting inside the cells before becoming active. Effectiveness of brand or generic Fludara has not yet been proved in non-refractory patients.
Precautions / Side Effects for Fludara
Fludara (Fludarabine phosphate) being an anti cancer drug should be administered and handled with due care. Your doctor will take appropriate steps in varying dosage or supplementing the treatment if your renal function is impaired, i.e., if the kidneys are not functioning satisfactorily. Your physicians will also evaluate weakened bone marrow and advanced age while recommending Fludara. Avoid alcohol, vaccination and drink more fluids. Defer having children by using condoms during sex. Have plenty of rest. Use softer tooth brush to prevent bleeding.
Some of the adverse side effects of treatment with brand or generic Fludara drug may disappear after completion of the treatment. It is generally possible to predict the duration and time when the side effects of medication may appear. The number of white or red blood cells and platelets in your blood may come down during brand or generic Fludara therapy. Consequently, you may be at a higher risk of anemia, infection or increased bleeding. If you are planning children, discuss it with the physician because Fludarabine phosphate may affect fertility in some cases.
Fludara drug is administered as an injection into the veins IV. The recommended dosage is 25 mg/m2 per day. The injection is given every day for five consecutive days. This five day cycle is repeated once in 28 days. Depending on the toxicity (hematologic or nonheamatologic), the dosage may be changed or delayed. 20% dose reduction is recommended in cases of weakened kidney function. The powder is reconstituted with 2 ml of clear sterile water for injection USP. The reconstituted injection should be used within eight hours. It should not be mixed with other drugs. Store the injection between 20 c and 8 0 C in a refrigerator.
Buy Fludara for injection From North Drug Store
At North Drug Store, we stock Fludara injection in 50 mg and 10mg dosage in each vial. Buy Fludara injection from North Drug Store to take maximum advantage of lower prices.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.