Shipping Update

We are now seeing improvements in our shipping times. However, things are not yet back to normal and there are still some delays occurring.

Our normal shipping time averages 1 - 2 weeks. Shipments may potentially take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

These delays are temporary, and we thank the shipping and delivery personnel who are working hard for all of us during this global crisis.

Please Note: We have resumed our normal 30-Day Shipping Guarantee. We will provide updates as the situation changes.

Call Center

Our call center hours of operation are 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.

Management and Staff
North Drugstore

Buy Paludrine from Canadian & International Pharmacies

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Paludrine (Proguanil Hydrochloride)

and/or alternatives
Brand Name Options

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Shipping is $10.00 per order. All prices are in USD. Average shipping time is 2 weeks.
Full information about Paludrine

General Information about Paludrine

Paludrine is an anti-malarial medicine. Malaria is caused by a parasite called plasmodium that is passed onto human blood from mosquitoes. Once this parasite enters the blood stream, it multiplies inside the red blood cells and begins it attack on the human body. The active drug present in Paludrine is proguanil hydrochloride. It directly acts on the parasites by blocking an enzyme called ‘dihydrofolate reductase’, which is involved in the reproduction of the plasmodium parasite. As a result, the drug prevents the growth of the malarial parasite. Paludrine tablets are essentially preventive in nature. In certain parts of the world, the plasmodium parasite has grown resistant to proguanil. For these areas, you cannot buy Paludrine as an effective medicine.

Side effects of Paludrine

The reaction to any particular drug and the risk of side effects vary greatly from person to person. The following side effects of Paludrine are among the most common. Different reactions may occur for certain people due to certain factors, such as their age, health condition etc.

  • problems in the stomach like constipation, diarrhoea, vomiting, nausea, abdominal pain ;
  • loss of hair (reversible) ;
  • angioedema ;
  • ulcers in the mouth ;
  • rashes and hives ;
  • vasculitis or inflammation of blood vessels ;

Apart from the aforementioned side effects, a few people may experience an allergic reaction to this drug. Beside proguanil hydrochloride, Paludrine contains gelatin, magnesium stearate, calcium carbonate and maize starch. An allergic reaction can be triggered if you are allergic to any of the above ingredients in the drug. Malaria can be very dangerous when it occurs during pregnancy. It is best to avoid malaria prone sites while carrying a baby. The drug passes on to breast milk, so you must discuss the risks involved with your doctor before you begin taking this medication. People suffering from liver or kidney problems are at a greater risk of suffering from side effects due to Paludrine.


Paludrine is available in the form of 100mg tablets. The first dose of Paludrine should start at least two days (preferably a week) before you go to a malaria prone area. At least 2 days are needed to ensure that there are traces of proguanil in the blood to fight the parasite. Medication should continue throughout the stay (it is best to ingest the tablet at the same time every day) in the affected region, and until 4 weeks have passed from the time you leave the region. One tablet per day should be consumed with food and never on an empty stomach. Paludrine is most effective when taken with chloroquine, which is a drug that kills the plasmodium parasite. The tablets should not be stored at a temperature exceeding 30 degree Celsius.


Patients rarely buy Paludrine as the sole medication for the prevention of malaria. Often, it is taken along with chloroquine. Both these medications interact widely with other drugs.

Paludrine increases the effect of anticoagulants, so both these drugs must not be taken at the same time. Antacids reduce the capacity of the body to absorb proguanil from the stomach and hence should be taken (if required) at least 2 hours before Paludrine is taken. Medicines to treat indigestion should be discontinued for the period. Alcohol and certain types of food are not known to interact with Paludrine.

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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.