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Prandimet (Repaglinide/Metformin Hydrochloride)

and/or alternatives
Prandimet is not available. Prandimet is a brand name for Repaglinide/Metformin Hydrochloride. Other generics of Repaglinide/Metformin Hydrochloride are available below.
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Full information about Prandimet

General Information on Prandimet

Prandimet is combination medication that contains two drugs with the generic names repaglinide and metformin. Both of them are diabetes medications that can help lower and maintain blood sugar levels.

Repaglinide affects the pancreas and stimulates it to produce insulin. The second drug, metformin, affects the liver and reduced glucose production. It also reduces the absorption of glucose in the intestines.

You can buy Prandimet as part of a complete treatment program for type 2, or non-insulin dependent, diabetes. Other aspects of the program would include diet and exercise.

Side effects of Prandimet

The most common side effect of Prandimet is low blood sugar, medically known as hypoglycemia. The symptoms of hypoglycemia would include sweating, hunger, weakness, irritability, tremors, concentration trouble, rapid heartbeat, seizures and fainting. You must always carry a glucose tablet or piece of hard candy in case you notice any signs of hypoglycemia.

Prandimet may also cause a condition known as lactic acidosis, which is a lactic acid buildup in the body that may be fatal. Lactic acidosis starts gradually, but it would worsen with time. You must inform your doctor immediately if you notice any signs of lactic acidosis, including the following:

  • Slow or uneven heart rate
  • Nausea, stomach pain, vomiting
  • Lightheadedness, dizziness, tiredness, weakness
  • Breathing trouble
  • Cold or numb feeling in the legs and arms
  • Muscle weakness or pain

Prandimet may also cause mild side effects, like those given below:

  • Diarrhea, nausea
  • Headache
  • Stuffy or runny nose, cough, sneezing and other common cold symptoms

Dosage of Prandimet

Prandimet is available as an oral tablet. You can buy Prandimet in the following dose strengths- 2mg repaglinide and 500mg metformin, and 1mg repaglinide and 500mg metformin. The dosage and duration of treatment with Prandimet would be determined by your doctor, and you must follow the prescribed treatment exactly.

In most cases, Prandimet us taken two or three times a day, and within 15 minutes of finishing a meal. However, your doctor may prescribe a different daily dosage. You may have to check your blood sugar level frequently while you are on Prandimet, and you have to undergo certain medical tests as well from time to time. Do not forget an appointment with your doctor.

If you are on Prandimet, then stay alert for signs of low blood sugar. Keep a source of sugar handy when you recognize the signs of hypoglycemia. You must continuously check and monitor your blood sugar levels, especially when you travel, exercise too much, skip meals or drink alcohol.

Interactions

Prandimet may interact with several medications. Therefore, it is important that you talk to your doctor before you start any drug while you are on Prandimet. Examples of medicines that interact adversely with Prandimet include Beta blockers like carvedilol, atenolol, metoprolol and propranolol. Other drugs that could interact with Prandimet include the following:

  • Heart and blood pressure drugs
  • Cyclosporine
  • Diuretics
  • NSAIDs

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