Buy Praxilene from Canadian & International Pharmacies
Praxilene (Naftidrofuryl Oxalate)and/or alternatives
Praxilene 100mg from $0.46 USD/capsulePraxilene 100mg
Manufactured by: Merck Serono UK
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
Naftidrofuryl Oxalate 100mg from $0.50 USD/capsuleNaftidrofuryl Oxalate 100mg
Generic Alternative to Praxilene
Manufactured by: A UK MHRA approved Generic Manufacturer
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
General Information on Praxilene
Praxilene is used for treating peripheral vascular disorders such as rest pain, intermittent claudication, incipient gangrene, Raynaud’s syndrome, night cramps, trophic ulcers, acrocyanosis and diabetic arteriopathy, and cerebral vascular disorders such as cerebral artherosclerosis and cerebral insufficiency.
The active ingredient in the medicine is Naftidrofuryl Oxalate. It works by widening the blood vessels and increasing the ability of the cells to get rid of waste matter. In this way, disorders caused due to decreased supply of blood in certain body parts are treated.
The medicine is available in the form of oral capsules, which you have to take exactly as prescribed by your doctor.
Side effects of Praxilene
Your doctor will not recommend you to buy Praxilene if you have an allergy to Naftidrofuryl Oxalate or to any of the drug’s ingredients. Also inform your doctor beforehand if you have recurrent calcium stones or history of hyperoxaluria. Also inform him or her if you have high blood pressure, diabetes, high cholesterol, liver or kidney disease, or a history of heart attack or stroke. Special tests will need to be taken and dosage adjustments will need to be made if you are suffering from any of these medical conditions.
Drink sufficient amount of liquids during Praxilene treatment, as you may have more chances of becoming dehydrated. As you may also be at risk of getting overheated, avoid sweating excessively due to strenuous physical activities such as jogging, exercise, or hot baths.
Praxilene is usually a well-tolerated medicine and side effects are rarely developed. However, some symptoms that Praxilene patients may experience include rashes, nausea or epigastric pain. Inform your doctor at once if any of these become intolerable.
Seek medical attention if you develop hepatitis or calcium oxalate kidney stones during Praxilene treatment even though these are rarely experienced side effects of the drug.
Some patients may also have an allergic reaction to Praxilene. Stop using the medicine at once if you develop hives, facial swelling, severe dizziness, or difficulty breathing after taking Praxilene. Seek medical attention if any of these symptoms persist even after discontinuing the drug.
Dosage of Praxilene
Praxilene 100mg is equal to 81mg Naftidrofuryl and 19mg oxalate. In order to treat peripheral vascular disorder, your doctor will advise you to take one or two Praxilene capsules three times a day, for a period of around 3 months. For treating cerebral vascular disorders, you will be advised to take one Praxilene 100mg capsule three times a day for around 3 months.
The capsules have to be swallowed whole, without opening, breaking or chewing them. Take the capsules with meals and along with a full glass of water.
Although no serious drug interactions have been reported so far, it would be better to inform your doctor about all the medicinal products you are using at present, including prescription and non-prescription drugs, herbal preparations and health supplements. Based on this information, your doctor will be able to decide whether he or she should recommend you to buy Praxilene or not and what dosage would be appropriate for you.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.