Buy Prempro from Canadian & International Pharmacies
Prempro (Estrogens, Conjugated/Medroxyprogesterone Acetate)and/or alternatives
Prempro 0.3/1.5mg from $1.29 USD/tabletPrempro 0.3/1.5mg
Marketed as Premique Low Dose in European Union
Manufactured by: Pfizer Ltd
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
Prempro 0.45/1.5mg from $6.90 USD/tabletPrempro 0.45/1.5mg
Manufactured by: Wyeth Ayerst Laboratories
Product of United States. Shipped from United StatesRxPrescription RequiredCurrently Unavailable
Prempro 0.625/5mg from $2.30 USD/tabletPrempro 0.625/5mg
Marketed as Premia in New Zealand
Manufactured by: Wyeth
Product of New Zealand. Shipped from VanuatuRxPrescription RequiredCurrently Unavailable
General Information on Prempro
Prempro is used for treating different conditions associated with menopause in women:
- Moderate or severe vasomotor symptoms
- Moderate or severe vulvar and vaginal atrophy
- Postmenopausal osteoporosis
This drug is a combination of medroxyprogesterone and conjugated estrogens. Conjugated estrogens are a combination of estrogen hormones that are essential for several processes in the female body. Medroxyprogesterone, also known as Progesterone, is needed for the processes of menstruation and ovulation.
You can buy Prempro in the form of oral tablets. It works by providing the necessary hormones to the patient’s body.
Side effects of Prempro
Before you buy Prempro, inform your doctor if you have any of the following medical conditions:
- Undiagnosed vaginal bleeding
- Cancer of the breast, uterus or ovaries
- Blood clots
- Liver or kidney disease
- Heart attack or heart disease
- Family history of cancer, breast lumps, angioedema or blood clots
- Blood clotting disorder such as protein S or protein C deficiency
- High blood pressure, high cholesterol or triglyceride, or diabetes
- Hormonal problem such as hypoparathyroidism
- Uterine problem such as endometriosis or fibroids
- Gall bladder disease
- Migraine headache
- Blood disorder such as porphyria
- Mental or mood problem such as depression or dementia
Your doctor will advise you to stop smoking or using tobacco during Prempro treatment, as these may increase your risks of high blood pressure, heart attack, stroke or blood clots, especially if you are more than 35 years of age.
Some common side effects associated with Prempro include breast tenderness, weight changes, headache, bloating, nausea, vomiting or stomach upset. These can be easily managed with or without medical help, but you should notify your doctor if any of these become too bothersome.
Prempro may sometimes cause a serious problem due to blood clotting, such as heart attack, deep vein thrombosis, stroke or pulmonary embolism. You should immediately seek medical attention if you develop any of the following symptoms:
- Chest, left arm or jaw pain
- Unusual sweating
- Sudden or severe headache
- Weakness on one side of the body
- Slurred speech
- Sudden changes in vision such as complete or partial blindness
- Pain, swelling or redness in legs
- Tingling, numbness or weakness in the arms or legs
- Difficulty breathing
- Sudden dizziness or fainting
- Coughing up blood
Dosage of Prempro
Each Prempro tablet contains 0.3mg of conjugated estrogens and 1.5mg of medroxyprogesterone. Usually, your doctor will advise you to take one tablet a day, with or without meals.
Try to take the tablet at almost the same time each day, and do not increase or decrease the dosage unless your doctor advises you to do so.
Some of the medicinal products that may interact with Prempro include aromatase inhibitors (e.g. letrozole, exemestane or anastrozole), antibiotics (e.g. erythromycin, clarithromycin or ketoconazole), barbiturates (e.g. Phenobarbital) or HIV medicines (e.g. ritonavir)
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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.