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Protonix (Pantoprazole Sodium)

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Full information about Protonix

Basic Information On Protonix

Protonix is used in the treatment of ulceration and erosion of the esophagus which is caused due to the gastro-esophageal reflux-disease (GERD). It belongs to proton pump inhibitor class of drugs. It is also referred to as anti-ulcer agents. The condition of erosive esophagitis is caused due to the acid in the stomach. It reduces the production of acid in the stomach. It is also used to treat other conditions that involve increased stomach acid for example Zollinger-Ellison syndrome. The drug acts by bonding to 2 sites of ATPase enzyme which is at the surface of parietal cells in the stomach. By doing this the brand or generic Protonix suppresses the last step of the production of gastric acid in the stomach.

Precautions / Side Effects For Protonix

Common side effects of Protonix are nausea vomiting, stomach pain, gas (or flatulence), diarrhea, dizziness, headache and joint pain. If these common side effects prolong or worsen, then consult your health care provider or physician. Serious side effects include symptoms of allergic reactions such as difficulty in breathing, hives, rashes and swelling in the throat, face, tongue or lips. If you experience these serious side effects with Pantoprazole then contact your health care provider immediately.

The drug may interact with other drugs such as: clopidogrel, blood thinning agents like warfarin, ketoconazole, or iron. Therefore, before you begin the therapy with the Protonix drug let your health care provider know about any medication that you are currently administering. Avoid the drug if you are hypersensitive or allergic to any of the drug’s components. Long term use of Pantoprazole in patients aged 50 years and above, especially at high doses may be lead to a risk of bone fractures especially in the spine, wrist and hip.

Protonix Dosage

In the treatment of Erosive esophagitis which is associated with GERD, the recommended dose of Protonix in adults is 40 mg administered daily once, for 8 weeks. In children aged > 5 years the recommended dose is 20 mg (for body weight > 15Kg to < 40Kg) and 40 mg (for body weight > 40Kg), administered daily once for 8 weeks. The maintenance dose of brand or generic Protonix for the healing process of Erosive esophagitis is recommended to be 40 mg administered daily once, in adults. In the treatment of Zollinger-Ellison syndrome, the dosage for adults is 40 mg administered daily twice.

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