Buy Renvela from Canadian & International Pharmacies
Renvela (Sevelamer Carbonate)and/or alternatives
Renvela 800mg from $1.96 USD/tabletRenvela 800mg
Manufactured by: Sanofi-Aventis
Product of United Kingdom. Shipped from United KingdomRxPrescription Required
Sevelamer Carbonate 800mg from $0.76 USD/tabletSevelamer Carbonate 800mg
Generic Alternative to Renvela
Marketed as Revlamer in India
Manufactured by: Emcure Ltd
Product of India. Shipped from IndiaRxPrescription Required
General Information on Renvela
Renvela is a medication indicated for the treatment and prevention of hypocalcemia, which is a medical condition characterized by the reduced level of body calcium. The generic name of Renvela is sevelamer, which belongs to a drug class known as phosphate binders.
Renvela works by reacting with phosphorus in the body, which reduces the level of phosphorus in the body. Hypocalcemia occurs as a result of abnormally high levels of phosphorus in the body. By curbing the phosphorus levels, Renvela prevents the onset of hypocalcemia.
Renvela is also indicated for the treatment of high blood phosphorus levels in patients diagnosed with chronic kidney disease and those undergoing dialysis.
Side effects of Renvela
You may not be able to take Renvela if you suffer from an bowel obstruction or if you have previously suffered from an allergy to sevelamar. You must inform your doctor if you experience the following before taking Renvela- severe constipation, swallowing problems, a diagnosed block in the intestines, intestinal or gastric disorders or if you have undergone any intestinal or stomach surgery.
The danger posed by Renvela for the fetus when it is taken during a pregnancy is not yet confirmed. You must talk to your doctor and discuss the risks involved for you and your baby before you are asked to buy Renvela. If you are breastfeeding a baby, you must also discuss the risks involved for the nursing baby before you begin taking Renvela.
Dosage of Renvela
Renvela must be taken in the exact dosage prescribed by your doctor for your condition. Your doctor may have to change the dosage prescribed based on your response to treatment. Renvela is available in the form of tablets and powder- and both are taken orally. The tablets are named Renvela 800mg, containing 800mg of sevelamer. The powder form of Renvela is available in sealed packs containing sevelamer 0.8g or sevelamer 2.4g. Renvela in the powder form is to be mixed with a liquid to form an oral suspension solution.
Renvela is recommended to be taken in three equal doses per day, usually accompanied with meals. This frequency is followed irrespective of the dosage prescribed by your doctor. In order to make an oral suspension of Renvela with its powder form, you must empty the entire contents of a packet of Renvela into a cup. Depending on the strength of Renvela powder, you must add the right amount of water into the cup and stir it well. If you are using a 0.8g packet, you must add 30ml of water. If you are taking the 2.4g packet, you must add 60ml of water.
If you are using the powder form of Renvela, you must mix and make the oral suspension only when you are ready to take the drug. Do not prepare the oral suspension beforehand and store it for later use.
Renvela is known to react and bind to other drugs, so you must avoid taking other medications for 1 hour before you take Renvela. You must also avoid taking drugs for 3 hours from the time you take Renvela. You must especially inform your doctor if you are taking seizure or heart rhythm medications before you buy Renvela.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.