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Saphris (Asenapine Maleate)

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Full information about Saphris

General Information on Saphris

Saphris is used to treat psychotic conditions such as schizophrenia and manic depression or bipolar disorder in adults. The generic name of this drug is Asenapine.

Saphris works by altering the action of chemicals in the patient’s brain. It is supplied for sublingual administration and comes in the form of tablets containing 5 mg Asenapine or 10 mg Asenapine. 5 mg Asenapine and 10 mg Asenapine black cherry flavored tablets are also available. The other inactive ingredients include mannitol and gelatin.

You can only buy Saphris online if your doctor has prescribed it for your treatment.

Side effects of Saphris

You should not buy Saphris if you have:

  • A hypersensitivity to Saphris or any other allergies such as breathing difficulty and swelling of the tongue, lips or face
  • A medical history of liver and heart problems such as a past heart attack, angina, or abnormal heartbeat
  • Severe dehydration
  • Drug/alcohol/substance addiction

Before you buy Saphris, inform your doctor if you have any of the following:

  • Seizures
  • Low white blood cell count
  • Stroke or Long QT syndrome
  • Diabetes
  • Breast cancer
  • Alzheimer’s disease
  • Dementia
  • Trouble swallowing
  • Parkinson’s disease

Some of the common and mild side effects of this drug are:

  • Drowsiness, dizziness
  • Numbness in or around the mouth
  • Sleeping problems
  • Constipation
  • Weight gain
  • Restlessness

You should consult your doctor immediately if your experience any of the following side effects:

  • Stiff muscles, confusion, sweating, uneven or fast heartbeat
  • Uncontrollable movements of the eyes, tongue, face, arms or legs
  • Tremors
  • Severe or sudden headache
  • Chills, body aches, flu symptoms
  • Hallucinations
  • Sores on the lips or inside the mouth

If taken during the last 3 months of pregnancy, Saphris can lead to withdrawal symptoms, feeding and breathing problems, fussiness, tremors, and stiff muscles in the newborn. In the case of nursing mothers, Saphris can pass into breast milk and harm a nursing baby.

Dosage of Saphris

Saphris is usually taken twice a day. A patient should keep this sublingual tablet under the tongue and allow it to get dissolved without crushing, chewing or swallowing it. A patient must not eat or drink anything for 10 minutes after taking the tablet.

The recommended dose of Saphris for the acute treatment of schizophrenia in adults is 5mg Saphris twice a day, which is increased to 10mg Saphris twice a day. The recommended dose for bipolar disorder is 10mg Saphris twice a day, which is reduced to 5 mg Saphris twice a day.

In case of a missed dose, a patient should take it as soon as he or she remembers to do so. If it is almost time for the next dose, he/she should skip the missed dose and take the medication at the next scheduled time. A patient should not overdose on Saphris to make up for the missed dose.


Many drugs interact with Saphris. These include any blood pressure medication, arsenic trioxide, tramadol, antibiotics, antidepressants, anti-malaria medications, and medicines to prevent or treat nausea, drugs to treat psychiatric disorders, migraine headache drugs, and narcotic medications.

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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.