Shipping Update – January 2022

Shipping times are now closer to normal. However, due to the latest outbreak of the highly contagious Omicron strain, we are anticipating some potential delays in our shipping times. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Shipments may now sometimes take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

Call Center – New Hours effective January 17, 2022

Our new call center hours of operation are now 7:00 am – 7:00 pm Central Time, seven days per week.

These changes are due to staffing issues we are experiencing caused by the highly contagious Omicron variant. We anticipate that we will expand our call center hours again within the next 2 – 3 weeks.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.

Management and Staff
North Drugstore

Buy Sentinel from Canadian & International Pharmacies

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Sentinel (Milbemycin Oxime/Lufenuron)

and/or alternatives
Brand Name Options

Low Price Guarantee

Delivery Guarantee

30 Day Returns

Shipping is $10.00 per order. All prices are in USD. Average shipping time is 2 weeks.
Full information about Sentinel

General Information on Sentinel

Sentinel is a flavored tablet which cures heartworm in dogs. One can buy Sentinel online only with a prescription from a veterinarian. Its beef flavor is made from proteins derived from soy and pork. It is the ideal monthly tablet for dogs and puppies who weigh at least two pounds and are four weeks old.

Sentinel flavored tablets contain Milbemycin oxime and Lufenuron. It is a versatile drug which eliminates roundworms, whipworms and hookworms along with heartworms. It works by breaking the gestation and adult stages of the larvae. The second ingredient Lufenuron is very effective in inhibiting the growth of fleas by destroying flea eggs and disrupting the lifecycle of the insect.

The worms destroyed are Ancylostoma caninum (hookworms), Dirofilaria immitis or heartworm, Toxocara canis (ascarids), and Trichuris vulpis (whipworms.) Dog lovers should consult their veterinarian and get a prescription to buy Sentinel as soon as possible because this is a monthly process which has to be carried out throughout the year. The drug can be easily mixed with food or given as a treat because of its flavored beef taste. It is the perfect protection against worms in the intestine. It is also safe for nursing or pregnant canine mothers.

Side effects of Sentinel

There are very rare reported side effects of Sentinel. Veterinarians can check for Milbemycin reactions before prescription to be on the safe side.

Vomiting and depression can surface in some dogs. In rare cases, it can lead to the loss of appetite and diarrhea.

Other dogs show signs of drowsiness on taking Sentinel. Seizures are also possible in rare cases. Itching and hives are also a possibility.

Special care should be given to the personal hygiene of the dog owner because roundworms and hookworms can be contracted by humans.

Dosage of Sentinel

Sentinel has to be administered once a month. It is preferable to give the medicine on the same date every month. If one forgets to give Sentinel, then it can be administered as soon as possible. The dose cannot be increased without the knowledge of the veterinarian.

Besides giving Sentinel to your pet every month, it is advisable to administer the drug all year round to ensure complete protection.

The common dosage for dogs in the weight range of 2lbs to 10lbs is 2.3mg/46mg. For dogs weighing 11lbs to 25 lbs, the recommended Sentinel dose is 5.75mg/115mg. 11.5mg/230mg is recommended for dogs weighing between 26lbs and 50lbs. Heavier dogs weighing up to 100lbs can be given a single dose of 23mg/460mg.


There are some medicines Sentinel may interact with. Caution is advised if the dog is getting antifungal treatment. Sentinel may interact with cyclosporine, ketoconazole, carvedilol, erythromycin, quinidine, clarithromycin, tamoxifen, diltiazem and spironolactone.

Sentinel should not be given if the same generic drug has been given as another branded medication. It also does not get rid of adult fleas. Separate treatment has to be given for such a condition. It is also recommended that raw meat not be given to the pet.

* All trademarks and registered trademarks are the property of their respective owners.

IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.