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Serophene (Clomiphene Citrate)

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Full information about Serophene

General Information on Serophene

Serophene is prescribed by a physician in cases of infertility in a woman. It acts as a stimulant to release hormones that are good for successful ovulation. Serophene is classified as an ovulatory agent. The medicine is generally prescribed by an obstetrician or a gynecologist; therefore one should not buy Serophene online without a prescription. The exact reason for infertility in a woman can be very complex, so one should only buy Serophene as per the advice of a physician.

Serophene consists of clomiphene citrate. It is an oral medicine and is generally prescribed by reproductive endocrinologists. Ovulation dysfunction can be treated with Serophene. It has a complex trigger system which results in the release of FSH (Follicle Stimulating Hormones.)

The complex system of messages kick started due to the use of Serophene begins with the hypothalamus starting the discharge of GnRH (gonadotropin releasing hormone). This is like a chain reaction, with the pituitary gland now releasing more FSH and LH (luteinizing hormone) to trigger the required follicle generation and necessary ovulation. Serophene is also recognized as a SERM (selective estrogen receptor modulator.)

The success of the treatment depends on the strict adherence to the dosage and schedule prescribed. This also involves the recording of body temperature, undergoing tests to detect ovulation, and trying for conception during the peak ovulation phases.

Side effects of Serophene

The use of Serophene can trigger an attack of OHSS (ovarian hyper stimulation syndrome.)

The medicine can also give rise to multiple births. It cannot be used by women suffering from excessive bleeding of the uterus. Any adrenal or thyroid problems also obviate the use of the drug.

Bloating, irritable stomach and hot flashes are very common side effects of the drug. Headaches, vomiting and vaginal bleeding can also occur as a result of Serophene. Any blurring of vision should be reported to the physician.

Women should ascertain whether they are pregnant or not before starting treatment with Serophene because it can be harmful to an unborn child.

Dosage of Serophene

The initial dose of Serophene in any treatment is always low. This can be limited to 5 days with a single tablet of 50 mg.

There is no need for an increase in dosage if ovulation occurs, otherwise the fertility specialist will increase the dosage as required.

If successful ovulation does not occur within the first five days, then another five day cycle of Serophene is to be observed with a double dose per day, that is, two tablets of 50 mg per day for five days, but only after the passage of 30 days. All required tests have to be conducted to ensure that the patient is not pregnant before starting the second treatment of five days. This can be done only to the extent of three times, after which Serophene treatment has to be discontinued.


Do not buy Serophene if you are on anti-psychotic drugs or all prolonging agents like Lopinavir, ciprofloxacin, thoridazine, pazopanib, tramadol, guanadrel, Quinine, sibutramine, mequinol, dronedarone, paliperidone, natisedine, pergolide, metrizamide, thioridazine, asenapine, saquinavir, halofantrine, sparfloxacin, toremifene, cisapride, droperidol and pimozide.

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