Buy Serophene from Canadian & International Pharmacies
Serophene (Clomiphene Citrate)and/or alternatives
Serophene 50mg from $2.00 USD/tabletSerophene 50mg
Manufactured by: Serono
Product of TurkeyRxPrescription RequiredCurrently Unavailable
Clomiphene Citrate 50mg from $0.59 USD/tabletClomiphene Citrate 50mg
Generic Alternative to Serophene
Marketed as Fertomid-50 in India
Manufactured by: Cipla
Product of India. Shipped from MauritiusRxPrescription Required
General Information on Serophene
Serophene is prescribed by a physician in cases of infertility in a woman. It acts as a stimulant to release hormones that are good for successful ovulation. Serophene is classified as an ovulatory agent. The medicine is generally prescribed by an obstetrician or a gynecologist; therefore one should not buy Serophene online without a prescription. The exact reason for infertility in a woman can be very complex, so one should only buy Serophene as per the advice of a physician.
Serophene consists of clomiphene citrate. It is an oral medicine and is generally prescribed by reproductive endocrinologists. Ovulation dysfunction can be treated with Serophene. It has a complex trigger system which results in the release of FSH (Follicle Stimulating Hormones.)
The complex system of messages kick started due to the use of Serophene begins with the hypothalamus starting the discharge of GnRH (gonadotropin releasing hormone). This is like a chain reaction, with the pituitary gland now releasing more FSH and LH (luteinizing hormone) to trigger the required follicle generation and necessary ovulation. Serophene is also recognized as a SERM (selective estrogen receptor modulator.)
The success of the treatment depends on the strict adherence to the dosage and schedule prescribed. This also involves the recording of body temperature, undergoing tests to detect ovulation, and trying for conception during the peak ovulation phases.
Side effects of Serophene
The use of Serophene can trigger an attack of OHSS (ovarian hyper stimulation syndrome.)
The medicine can also give rise to multiple births. It cannot be used by women suffering from excessive bleeding of the uterus. Any adrenal or thyroid problems also obviate the use of the drug.
Bloating, irritable stomach and hot flashes are very common side effects of the drug. Headaches, vomiting and vaginal bleeding can also occur as a result of Serophene. Any blurring of vision should be reported to the physician.
Women should ascertain whether they are pregnant or not before starting treatment with Serophene because it can be harmful to an unborn child.
Dosage of Serophene
The initial dose of Serophene in any treatment is always low. This can be limited to 5 days with a single tablet of 50 mg.
There is no need for an increase in dosage if ovulation occurs, otherwise the fertility specialist will increase the dosage as required.
If successful ovulation does not occur within the first five days, then another five day cycle of Serophene is to be observed with a double dose per day, that is, two tablets of 50 mg per day for five days, but only after the passage of 30 days. All required tests have to be conducted to ensure that the patient is not pregnant before starting the second treatment of five days. This can be done only to the extent of three times, after which Serophene treatment has to be discontinued.
Do not buy Serophene if you are on anti-psychotic drugs or all prolonging agents like Lopinavir, ciprofloxacin, thoridazine, pazopanib, tramadol, guanadrel, Quinine, sibutramine, mequinol, dronedarone, paliperidone, natisedine, pergolide, metrizamide, thioridazine, asenapine, saquinavir, halofantrine, sparfloxacin, toremifene, cisapride, droperidol and pimozide.
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What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.