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Silvadene (Silver Sulfadiazine)

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Silvadene is not available. Silvadene is a brand name for Silver Sulfadiazine. Other brands and generics of Silver Sulfadiazine are available below.
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Full information about Silvadene

General Information on Silvadene

Silvadene is an antibiotic. It fights bacterial and fungal infections on the skin. It is an adjunct for the treatment and prevention of wound sepsis in patients with second and third degree burns. The generic name of this drug is Silver Sulfadiazine Topical and the other brand names are Thermazene, SSD and SSD AF.

Silvadene acts as an antimicrobial agent. This cream consists of stearyl alcohol, white petrolatum, sorbitan monooleate, isopropyl myristake, propylene glycol, etc. with 0.3% methylparaben. This medication is available in jars containing Silvadene 50g, Silvadene 400g, Silvadene 1000g and tubes containing Silvadene 20g and Silvadene 85g.

Silvadene is essentially a sulfonamide. It kills bacteria by working on the microorganisms’ cell wall and cell membrane.

You can only buy Silvadene as per a doctor’s prescription.

Side effects of Silvadene

You should not buy Silvadene online if any of the following conditions are true:

  • You are hypersensitive to any ingredient used in Silvadene
  • You are pregnant or you are nearing your delivery date
  • You are taking methenamine

Before you buy Silvadene, inform your doctor if any of the following are true:

  • If you are nursing a baby or pregnant
  • If you have any allergies to foods, medicines or other substances, especially sulfonamides
  • If you suffer from kidney disease
  • If you have liver problems

Some of the common, and mild, side effects of this drug are:

  • Burning
  • Hives
  • Itching
  • Rash
  • Redness
  • Skin discoloration

You should consult your doctor immediately if your experience any of the following side effects:

  • Severe allergic reactions
  • Difficulty breathing
  • Difficulty urinating

Pregnant women can use Silvadene if recommended by doctor. Nursing mothers should avoid this medication since it can pass into breast milk and may harm a nursing baby.

Dosage of Silvadene

It is recommended that you apply Silvadene with an approximate thickness of 1/6 inch once or twice a day to the burn areas. The treated areas should have a layer this cream at all times. To clear up the infection completely, a patient has to continue using Silvadene for the full course of treatment even if patient’s condition improves.

In case of a missed dose, patient should apply the missed dose as soon as he or she remembers. You can continue with your regular schedule if it almost time for the next dose of medicine to be applied. Do not use apply Silvadene twice consecutive to make up. In case of an overdose of Silvadene, you may need emergency medical help.


There are 3 drug interactions and 7 disease interactions with Silvadene. These include; hematologic toxicity, hypersensitivity reaction, porhyria, crystalluria, liver disease, renal dysfunction and urinary obstruction.

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