Buy Simponi from Canadian & International Pharmacies
Simponi (Golimumab)and/or alternatives
General Information on Simponi
Simponi, or Simponi SmartJect, is used to treat psoriatic arthritis, rheumatoid arthritis and ankylosing spondylitis. It is a solution for subcutaneous injection and it works by reducing effects of certain substances in the body that can lead to an inflammation. The generic name of this drug is Golimumab.
Each 0.5ml of this drug contains 50mg Golimumab, , 0.8mg of polysorbate 80, 20.5mg of sorbitol, 0.44mg of L-histidine, and water. This medication is only available as Simponi 50mg/0.5 ml.
You can only buy Simponi as per a doctor’s prescription.
Side effects of Simponi
You should not buy Simponi online if you have:
- A known hypersensitivity to Golimumab or if you are using adalimumab, certolizumab, etanercept or infliximab
- A medical history of an active infection, fungal infections and TB infection
- Heart disease or decreased bone marrow function
- Certain brain or spinal cord disorders
Before you buy Simponi, inform your doctor if you have any of the following:
- Signs of an active infection, such as fever, sore throat, flu symptoms, chills
- Hepatitis B
- Multiple sclerosis
- HIV or weak immune system
- Recently been vaccinated with BCG
Some of the common but mild side effects of this drug are:
- Cold symptoms such as sneezing, sore throat and stuffy nose
- Redness where medicine is injected
You should consult your doctor immediately if your experience any of the following side effects:
- Night sweats, weight loss, fever, tiredness
- Pale skin, easy bruising or bleeding
- Shortness of breath with swelling of feet or ankles
- Weakness in legs, numbness feeling
- A butterfly shaped skin rash over nose and cheeks
- Nausea, stomach pain, loss of appetite, clay-colored stools, jaundice
Pregnant women can take Simponi only with recommendation of doctor. Nursing mothers should take this medication only with doctor’s prescription.
Dosage of Simponi
The recommended dose is Simponi 50mg a month which is to be administered by subcutaneous injection. For patients with rheumatoid arthritis, Simponi is given in combination with methotrexate and for patients with psoriatic arthritis or ankylosing spondylitis; this medication may be given with or without methotrexate or other non biologic DMARDs.
Each administration of this medicine has to be given at different places on the stomach, upper arm and thigh. Simponi is injected under the skin. A patient should not self inject this injection if he or she does not fully understand how to give the injection and properly dispose used needles and syringes.
In case of a missed dose, a patient should use the medication as soon as he or she remembers and then go back to his or her regular injection schedule. A patient should not take extra medicine to make up the missed dose. In case of an overdose, a patient should seek emergency medical assistance.
Drugs like abatacept, anakinra, rituximab, warfarin, cyclosporine, digoxin, theophylline, seizure medication such us carbamazepine, divalproex, or valproic acid and a heart rhythm medication such as disopyramide, quinidine and procainamide, may have adverse reaction if used with Simponi. A patient should not take a live vaccine while being treated with Simponi.
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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have the comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo comparative testing to ensure that they are the same as their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain comparable active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must be comparable in strength and dosage to the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically comparable. They may look different, and be called something different, but they are required to be have the same active ingredient.
How are Generic drugs tested to ensure quality and efficacy?
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.