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Sinequan (Doxepin Hydrochloride)

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  1. Doxepin Hydrochloride 50mg is currently unavailable from New Zealand

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Full information about Sinequan

General Information on Sinequan

Sinequan belongs to a drug known as tricyclic antidepressants. It is used to treat symptoms of depression and/or anxiety in psychoneurotic patients or those associated with alcoholism, psychotic depressive disorders or manic depressive conditions. The generic name of this drug is Doxepin.

The inert ingredients for Sinequan capsule are magnesium stearate, starch, sodium lauryl sulfate and for oral concentrate Sinequan ingredients are glycerin, methylparaben, peppermint oil, propylparaben and water. This medication is available as capsule in the following strengths, Sinequan 10mg, Sinequan 25mg, Sinequan 50mg, Sinequan 75mg, Sinequan 100mg and Sinequan 150mg.

You can only buy Sinequan as per a doctor’s prescription.

Side effects of Sinequan

You should not buy Sinequan online if you have:

  • A known hypersensitivity to Doxepin
  • Glaucoma with urination
  • Used an MAO inhibitor such as furazolidone, isocarboxazid, phenelzine, within past 14 days

Before you buy Sinequan, inform your doctor if you have any of the following:

  • Sleep apnea
  • Bipolar disorder or manic-depression
  • Diabetes
  • Less than 24 years of age

Some of the common, and mild, side effects of this drug are:

  • Feeling dizzy, drowsy
  • Nausea, vomiting, diarrhea, loss of appetite
  • Weight gain
  • Blurred vision, headache, ringing in ears
  • Decreased sex drive

You should consult your doctor immediately if your experience any of the following side effects:

  • Restless muscle movements in eyes, jaw, neck or tongue
  • Urinating less than usual or not at all
  • Extreme thirst with headache and weakness
  • Unusual bleeding from nose, mouth, vagina or rectum
  • Hallucinations, confusion, seizure

Pregnant women can take Sinequan only with a doctor’s prescription. Nursing mothers should take this medication only under the supervision of a doctor.

Dosage of Sinequan

The recommended dose for patients with mild to moderate illness is Sinequan 75mg. The Dosage can be subsequently reduced or increased at appropriate intervals corresponding to the patient’s response. The usual dose range is 75mg of Sinequan a day to 150mg of Sinequan a day.

In patients with severe medical conditions, the dose is gradually increased to 300 mg /day Sinequan if necessary. And patients with very mild emotional symptoms are provided as low as Sinequan 25mg a day to Sinequan 50mg a day. However, a once-a-day schedule if employed, the maximum recommended dose is Sinequan 150mg a day.

In case of a missed dose, a patient should use the medication as soon as he or she remembers. If it is almost time for next scheduled dose, a patient should skip the missed dose. A patient should not take extra medicine to make up the missed dose. In case of an overdose, symptoms such as hallucinations, muscle stiffness, blurred vision, uneven heartbeats may occur which need emergency medical help.


There are 959 drugs which interact with Sinequan, out of which 235 have major, 663 moderate and 61 minor drug interactions with Sinequan. Drugs like cimetidine, tolazamide, heart rhythm medications and phenothiazines may have adverse reactions with Sinequan. There are 9 disease interactions with Sinequan which include anticholinergic effects, cardiovascular disease, pheochromocytoma, seizure disorders, bone marrow suppression, diabetes, renal/liver disease, schizophrenia/bipolar disorder and Tardive Dyskinesia. Alcohol has a moderate drug interaction with Sinequan.

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IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.