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Treximet (Sumatriptan Succinate/Naproxen Sodium)

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Full information about Treximet

General Information on Treximet

Treximet is a medication that contains two active ingredients with the generic names naproxen and sumatriptan. While sumatriptan is a headache medication, naproxen belong to the drug class known as NSAIDs or non-steroidal anti-inflammatory drugs.

You can buy Treximet online for the treatment of migraine headaches. Treximet works in two ways- sumatriptan narrows the blood vessels that surround the brain and naproxen reduces the action of hormones responsible for pain and inflammation in the body.

It is important for you to understand that you can buy Treximet only for treating headaches that have already started. It cannot be used for preventing attacks or reducing their frequency.

Side effects of Treximet

You cannot take two tablets of Treximet within a period of 24 hours. This may result in an overdose, signs of which include the following:

  • Seizure
  • Coughing up blood
  • Bloody or black stools
  • Breathing problems
  • Vomiting
  • Nausea
  • Stomach pain
  • Heartburn
  • Drowsiness
  • Dizziness

You would need immediate medical intervention if you suffer from an overdose of Treximet. Other serious side effects caused by Treximet include the following:

  • Agitation, fever, hallucinations, overactive reflexes, loss of coordination, fainting (these side effects occur if you are taking antidepressant medications along with Treximet)
  • Severe redness, peeling, or blistering of skin
  • Tingling, numbness, or bluish appearance in the toes or fingers
  • Pale skin, flu symptoms, easy bruising, weakness
  • Reduced or no urination, swelling, or rapid weight gain
  • Upper stomach pain, nausea, dark colored urine or clay colored stools, nausea

Dosage of Treximet

You can buy Treximet in the form of oral tablets, each of which contains sumatriptan 85mg and naproxen 500mg. The dosage and treatment schedule will be determined only by your doctor. Do not take a larger dosage of Treximet than what was prescribed, as it may worsen your migraine headaches.

You may take one tablet of Treximet when you notice symptoms of a migraine headache or once the attack has begun. This medication may be taken irrespective of whether you had meals or not.


Treximet is known to interact with several medications. As a result, you cannot take Treximet for a period of 24 hours before and after taking the following drugs:

  • Almotriptan
  • Eletriptan
  • Frovatriptan
  • Naratriptan
  • Rizatriptan
  • Sumatriptan
  • Zolmitriptan
  • Ergot medications such as ergotamine, dihydroergotamine and methylergonovine

You must tell your doctor about all the medications you are taking before you buy Treximet. A lot of combination medications have drugs in them that work like naproxen, such as ketoprofen or ibuprofen. By taking such medications along with Treximet, you are increasing your risk of an overdose. You must be careful while choosing any medication and check beforehand if it contains naproxen, ketoprofen, ibuprofen or aspirin.

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