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Tygacil (Tigecycline)

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Full information about Tygacil

Basic Information On Tygacil

Tygacil is an injectable glycylcycline antibacterial drug. It is a semi-synthetic derivative of minocycline. This medication acts against tetracycline-resistant gram-positive and gram-negative pathogens. It is used to treat infections of the skin, soft tissues and intra-abdominal infections caused by susceptible bacteria. It is injected intravenously. The Tygacil drug attaches to bacterial ribosomes and stops the production of proteins required for the growth and multiplication of the bacteria. This medicine is also able to overcome typical bacterial resistance to tetracyclines. Its modification at position 9 of its core structure, gives additional steric hindrance to it. Therefore, Tygacil has a much wider range of activity than conventional tetracyclines. However, it only prevents multiplication of the bacteria; it does not kill the bacteria.

Precautions / Side Effects Of Tygacil

Tygacil contains Tigecycline. It should not be administered to patients hypersensitive to Tigecycline or other tetracycline class antibiotics. It is structurally similar to tetracycline-class antibiotics and may cause adverse side effects like: anti-anabolic action (which has led to increased BUN, azotemia, acidosis, and hyperphosphatemia), photosensitivity, and pseudotumor cerebri. Using this drug during tooth development can cause permanent staining or discoloration of teeth. Brand or generic Tygacil should not be given to patients below 18 and breast feeding women.

In isolated cases, brand or generic Tygacil may lead to hepatic dysfunction and hepatic failure. Special caution should be exercised while administering this medication to patients with liver disorders. Its effects may persist even after the medication has been discontinued. Tigecycline should be used only in treating infections strongly suspected to be caused by susceptible bacteria. Using this drug may also result in the overgrowth of non-susceptible organisms like fungi. This medication must not be used by pregnant women as it can injure the fetus.

Tygacil Dosage

The recommended initial dosage for Tygacil is 100 mg. It is followed by a 50 mg dose every 12 hours. Intravenous infusions of this medication should be administered over 30 to 60 minutes at intervals of 12 hours. For the treatment of severe intra-abdominal infections or skin and skin structure infections this medication should be given for 5 to 14 days. For the treatment of community-acquired bacterial pneumonia, the duration of treatment should be 7 to 14 days. The medication dosage should be adjusted for patients with severe hepatic impairment. The duration of treatment is based on the severity and the site of infection. It also depends on the patient’s clinical and bacteriological improvement.

Buy Tygacil From North Drug Store

North Drug Store supplies brand or generic Tygacil as 50 mg injections. You can buy Tygacil from North Drug Store, as we are a online prescription service and offer a low price guarantee.

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