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Valdoxan (Agomelatine)

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Full information about Valdoxan

General Information On Valdoxan

Valdoxan is a prescription drug used to treat acute depression. The generic name of this drug is Agomelatin, which belongs to the class of antidepressant medicines. It is usually available in Valdoxan 25 mg strength. One must note that Valdoxan cannot eliminate depression immediately after a dose is taken. Therefore, patients who decide to buy Valdoxan online or from a pharmacy after getting a doctor’s prescription need to exercise patience as the results surface only after around 2 weeks of regular usage, if not longer.

Each Valdoxan tablet contains, besides 25 mg of the active ingredient agomelatin, certain inactive substances. These are- lactose, povidone, sodium starch glycollate, stearic acid, hypromellose, silica, glycerol, shellac, maize, magnesium stearate, iron oxide yellow, macrogol 6000 and titanium dioxide, propylene glycol, and indigo carmine.

Side Effects of Valdoxan

Agomelatin may not be the right drug for patients with an impaired liver. Those who are prone to violent and suicidal thoughts and suffer from psychological disorders like hypomania or mania, bipolar disorder, dementia, etc. need to discuss the effects of the drug with their doctor before they buy Valdoxan. Valdoxan is contraindicated in alcoholics and those who are already on other antidepressants. Pregnant and nursing women should only buy Valdoxan after talking to their doctor about the risks and benefits of using the medication. Valdoxan is not meant for use by children below 18 years of age, and extreme caution should be exercised while administering the drug to a young adult. All patients using Valdoxan should regularly visit their doctors for check-ups.

Some of the minor effects that may be experienced with Valdoxan are as follows:

  • Dizziness
  • Somnolence
  • Insomnia
  • Migraine or severe headache
  • Diarrhea or constipation and other gut problems
  • Hyperhidrosis or increased sweating
  • Backache
  • Tiredness
  • Anxiety and sudden mood shifts
  • Pins and needles in the limbs
  • Blurred vision
  • Eczema

The above list does not cover all the side effects of Valdoxan. Some of the more potent side effects of the drug are :

  • Jaundice
  • Easy bruising and bleeding
  • Loss of consciousness
  • Confusion
  • Hallucinations
  • Hepatitis
  • Severe skin rashes and eruptions
  • Major depression and suicidal thoughts
    • All the aforementioned side effects need to be reported immediately to the doctor. There may be effects of the drug on some patients beside the ones mentioned above.

      Dosage of Valdoxan

      The usual prescribed dose of Valdoxan is one or two 25 mg tablets at bedtime. However, this can change as per the discretion of the doctor and the patient’s requirement. The pills should be swallowed whole with water. Missing a dose can hinder the efficacy of Valdoxan treatment. However, doses should not be doubled to make up for the missed dose. In case of an overdose, contact your doctor immediately. Valdoxan should be stored at temperature, not exceeding 30 degrees Celsius.


      Valdoxan has been known to interact with fluvoxamine (an antidepressant) and an antibiotic called ciprofloxacin. A doctor needs to know about all the medicines a patient is taking so as to avoid harmful interactions. Alcohol also tampers with the functioning of Valdoxan and harms the liver during treatment.

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